Sepsis is a highly lethal syndrome resulting from dysregulated immune and metabolic
responses to infection, thereby compromising host homeostasis. Activation of the …

Sepsis is an acute systemic inflammatory disease. Glucocorticoids (GCs), which function by
binding to the GC receptor GR have very powerful anti-inflammatory activities, yet they are …

Abstract p53 regulates several signaling pathways to maintain the metabolic homeostasis of
cells and modulates the cellular response to stress. Deficiency or excess of nutrients causes …

Epidemiological evidence indicates that thyroid stimulating hormone (TSH) is positively
correlated with abnormal glucose levels. We previously reported that TSH has direct effects …

The liver plays an important role in inflammation and stress by producing the acute phase
proteins (APPs) required for resolution of inflammation as well as by delivering systemic …

The glucocorticoid receptor (GR) is a ligand-dependent transcription factor that mediates the
effects of glucocorticoids, and plays a crucial role in cell growth, development, inflammation …

Endotoxic hypoglycaemia has an important role in the survival rates of septic patients.
Previous studies have demonstrated that hypothalamic AMP-activated protein kinase (hyp …

Disturbed homeostasis as a result of tissue stress can provoke leukocyte responses
enabling recovery. Since mild hypothermia displays specific clinically relevant tissue …

Objectives To investigate whether lipopolysaccharide (LPS) is present in plasma of calves
with naturally occurring diarrhea. The second objective was to determine whether plasma …

Результаты. Снижение уровня гормонов щитовидной железы оказывает влияние на
печень, вызывая изменения в углеводном обмене, например, в качестве антагонистов …