Natural bone constitutes a complex and organized structure of organic and inorganic
components with limited ability to regenerate and restore injured tissues, especially in large …

Hydrogels are three-dimensional, cross-linked, and supramolecular networks that can
absorb significant volumes of water. Hydrogels are one of the most promising biomaterials in …

The development of lipid nanoparticle (LNP) formulations for targeting the bone
microenvironment holds significant potential for nucleic acid therapeutic applications …

Collagen hydrogels are among​ the most well-studied platforms for drug delivery and in situ
tissue engineering, thanks to their low cost, low immunogenicity, versatility, biocompatibility …

This Review presents polysaccharides, oligosaccharides, nucleic acids, peptides, and
proteins as functional stimuli‐responsive polymer scaffolds that yield hydrogels with …

Repair of bone defects is a time-consuming, self-healing process based on tissue modeling
and remodeling. However, the capacity of this method is limited, especially for critical-sized …

Bone is a hard yet dynamic tissue with remarkable healing capacities. Research to date has
greatly advanced the understanding of how bone heals and has led to marked success in …

3D bioprinting has recently emerged as a very useful tool in tissue engineering and
regenerative medicine. However, developing suitable bioinks to fabricate specific tissue …

The design of hydrogels with adequate mechanical properties and excellent bioactivity,
osteoconductivity, and capacity for osseointegration is essential to bone repair and …

Injuries of bone and cartilage constitute important health issues costing the National Health
Service billions of pounds annually, in the UK only. Moreover, these damages can become …