Mitochondrial ROS metabolism: 10 years later
AY Andreyev, YE Kushnareva, AN Murphy… - Biochemistry …, 2015 - Springer
The role of mitochondria in oxidative stress is well recognized, but many questions are still to
be answered. This article is intended to update our comprehensive review in 2005 by …
be answered. This article is intended to update our comprehensive review in 2005 by …
[HTML][HTML] Positive oxidative stress in aging and aging-related disease tolerance
LJ Yan - Redox biology, 2014 - Elsevier
It is now well established that reactive oxygen species (ROS), reactive nitrogen species
(RNS), and a basal level of oxidative stress are essential for cell survival. It is also well …
(RNS), and a basal level of oxidative stress are essential for cell survival. It is also well …
The 2-oxoacid dehydrogenase complexes in mitochondria can produce superoxide/hydrogen peroxide at much higher rates than complex I
CL Quinlan, RLS Goncalves, M Hey-Mogensen… - Journal of Biological …, 2014 - ASBMB
Several flavin-dependent enzymes of the mitochondrial matrix utilize NAD+ or NADH at
about the same operating redox potential as the NADH/NAD+ pool and comprise the …
about the same operating redox potential as the NADH/NAD+ pool and comprise the …
[HTML][HTML] Pyruvate dehydrogenase complex and nicotinamide nucleotide transhydrogenase constitute an energy consuming redox circuit
KH Fisher-Wellman, CT Lin, TE Ryan… - The Biochemical …, 2015 - ncbi.nlm.nih.gov
Cellular proteins rely on reversible redox reactions to establish and maintain biological
structure and function. How redox catabolic (NAD+: NADH) and anabolic (NADP+: NADPH) …
structure and function. How redox catabolic (NAD+: NADH) and anabolic (NADP+: NADPH) …
Hydrogen-deuterium exchange mass spectrometry: A novel structural biology approach to structure, dynamics and interactions of proteins and their complexes
O Ozohanics, A Ambrus - Life, 2020 - mdpi.com
Hydrogen/Deuterium eXchange Mass Spectrometry (HDX-MS) is a rapidly evolving
technique for analyzing structural features and dynamic properties of proteins. It may stand …
technique for analyzing structural features and dynamic properties of proteins. It may stand …
[HTML][HTML] Mild oxidative stress is beneficial for sperm telomere length maintenance
S Mishra, R Kumar, N Malhotra, N Singh… - World journal of …, 2016 - ncbi.nlm.nih.gov
AIM: To evaluate telomere length in sperm DNA and its correlation with oxidative stress
(normal, mild, severe). METHODS: The study included infertile men (n= 112) and age …
(normal, mild, severe). METHODS: The study included infertile men (n= 112) and age …
Formation of reactive oxygen species by human and bacterial pyruvate and 2-oxoglutarate dehydrogenase multienzyme complexes reconstituted from recombinant …
Individual recombinant components of pyruvate and 2-oxoglutarate dehydrogenase
multienzyme complexes (PDHc, OGDHc) of human and Escherichia coli (E. coli) origin were …
multienzyme complexes (PDHc, OGDHc) of human and Escherichia coli (E. coli) origin were …
Human dihydrolipoamide dehydrogenase (E3) deficiency: Novel insights into the structural basis and molecular pathomechanism
A Ambrus, V Adam-Vizi - Neurochemistry international, 2018 - Elsevier
This review summarizes our present view on the molecular pathogenesis of human (h) E3-
deficiency caused by a variety of genetic alterations with a special emphasis on the …
deficiency caused by a variety of genetic alterations with a special emphasis on the …
Protein redox modification as a cellular defense mechanism against tissue ischemic injury
LJ Yan - Oxidative medicine and cellular longevity, 2014 - Wiley Online Library
Protein oxidative or redox modifications induced by reactive oxygen species (ROS) or
reactive nitrogen species (RNS) not only can impair protein function, but also can regulate …
reactive nitrogen species (RNS) not only can impair protein function, but also can regulate …
Targeting the Achilles' heel of cancer cells via integrin-mediated delivery of ROS-generating dihydrolipoamide dehydrogenase
A Dayan, G Fleminger, O Ashur-Fabian - Oncogene, 2019 - nature.com
Cancer cells frequently exhibit higher levels of reactive oxygen species (ROS) than normal
cells and when ROS levels increase beyond a cellular tolerability threshold, cancer cell …
cells and when ROS levels increase beyond a cellular tolerability threshold, cancer cell …