Targeting the gut microbiota for cancer therapy

MR Fernandes, P Aggarwal, RGF Costa… - Nature Reviews …, 2022 - nature.com
Growing evidence suggests that the gut microbiota modulates the efficacy and toxicity of
cancer therapy, most notably immunotherapy and its immune-related adverse effects. The …

Impact of bacterial metabolites on gut barrier function and host immunity: a focus on bacterial metabolism and its relevance for intestinal inflammation

N Gasaly, P De Vos, MA Hermoso - Frontiers in immunology, 2021 - frontiersin.org
The diverse and dynamic microbial community of the human gastrointestinal tract plays a
vital role in health, with gut microbiota supporting the development and function of the gut …

[HTML][HTML] Gut microbiota-derived short chain fatty acids are potential mediators in gut inflammation

M Akhtar, Y Chen, Z Ma, X Zhang, D Shi, JA Khan… - Animal nutrition, 2022 - Elsevier
Gut inflammation is a challenging concern in humans and animals, which disturbs normal
growth and leads to severe bowel diseases. Short chain fatty acids (SCFA) are the gut …

The dietary fiber pectin: health benefits and potential for the treatment of allergies by modulation of gut microbiota

F Blanco-Pérez, H Steigerwald, S Schülke… - Current allergy and …, 2021 - Springer
Abstract Purpose of Review The incidence of allergies is increasing and has been
associated with several environmental factors including westernized diets. Changes in …

Extraction, characterization, and applications of pectins from plant by-products

A Belkheiri, A Forouhar, AV Ursu, P Dubessay… - Applied Sciences, 2021 - mdpi.com
Currently, pectins are widely used in the cosmetic, pharmaceutical, and food industries,
mainly as texturizing, emulsifying, stabilizing, and gelling agents. Pectins are …

Pectic polysaccharides: Targeting gut microbiota in obesity and intestinal health

HB Lee, YS Kim, HY Park - Carbohydrate polymers, 2022 - Elsevier
The gut microbiome is a complex ecosystem of the host body that maintains a balance with
its host. In this context, dysbiosis can lead to inflammatory response, immune dysregulation …

Role of dietary fiber in promoting immune health—An EAACI position paper

C Venter, RW Meyer, M Greenhawt, I Pali‐Schöll… - Allergy, 2022 - Wiley Online Library
Microbial metabolism of specific dietary components, such as fiber, contributes to the
sophisticated inter‐kingdom dialogue in the gut that maintains a stable environment with …

Gut microbiota-motility interregulation: insights from in vivo, ex vivo and in silico studies

B Waclawiková, A Codutti, K Alim, S El Aidy - Gut microbes, 2022 - Taylor & Francis
The human gastrointestinal tract is home to trillions of microbes. Gut microbial communities
have a significant regulatory role in the intestinal physiology, such as gut motility. Microbial …

[HTML][HTML] The European Polysaccharide Network of Excellence (EPNOE) research roadmap 2040: Advanced strategies for exploiting the vast potential of …

M Gericke, AJR Amaral, T Budtova, P De Wever… - Carbohydrate …, 2024 - Elsevier
Polysaccharides are among the most abundant bioresources on earth and consequently
need to play a pivotal role when addressing existential scientific challenges like climate …

Fostering next-generation probiotics in human gut by targeted dietary modulation: An emerging perspective

M Kumari, P Singh, BH Nataraj, A Kokkiligadda… - Food research …, 2021 - Elsevier
Emerging evidence and an in-depth understanding of the microbiome have helped in
identifying beneficial commensals and their therapeutic potentials. Specific commensal …