Imaging in Spaceflight Associated Neuro-ocular Syndrome (SANS): current technology and future directions in modalities

B Soares, J Ong, E Waisberg, P Sarker… - Life Sciences in Space …, 2024 - Elsevier
With plans for future long-duration crewed exploration, NASA has identified several high
priority potential health risks to astronauts in space. One such risk is a collection of …

Advanced diffusion MRI of the visual system in glaucoma: From experimental animal models to humans

M Mendoza, M Shotbolt, MA Faiq, C Parra, KC Chan - Biology, 2022 - mdpi.com
Simple Summary This review summarizes current applications of advanced diffusion
magnetic resonance imaging (MRI) throughout the glaucomatous visual system, focusing on …

Preliminary diffusion‐tensor imaging evidence for trans‐synaptic axonal degeneration in dysthyroid optic neuropathy due to thyroid‐associated ophthalmopathy

P Liu, B Luo, L Chen, QX Wang, LH Zhai… - Journal of Magnetic …, 2023 - Wiley Online Library
Background The mechanism driving dysthyroid optic neuropathy (DON) is unclear. Diffusion‐
tensor imaging (DTI) allows for noninvasively assessing the microstructure of the entire …

Machine learning analysis reveals abnormal functional network hubs in the primary angle-closure glaucoma patients

RB Chen, YL Zhong, H Liu, X Huang - Frontiers in Human …, 2022 - frontiersin.org
Background Primary angle-closure glaucoma (PACG) is a serious and irreversible blinding
eye disease. Growing studies demonstrated that PACG patients were accompanied by …

[HTML][HTML] Evaluation of trabecular meshwork-specific promoters in vitro and in vivo using scAAV2 vectors expressing C3 transferase

JK Tan, Y Xiao, G Liu, LX Huang, WH Ma… - International Journal …, 2023 - ncbi.nlm.nih.gov
AIM To evaluate the potential of two trabecular meshwork (TM)-specific promoters, Chitinase
3-like 1 (Ch3L1) and matrix gla protein (MGP), for improving specificity and safety in …

Application of diffusion tensor imaging technology in glaucoma diagnosis

J Wang, Y Zhang, X Meng, G Liu - Frontiers in neuroscience, 2023 - frontiersin.org
Glaucoma is the first major category of irreversible blinding eye illnesses worldwide. Its
leading cause is the death of retinal ganglion cells and their axons, which results in the loss …

Reverse translation of artificial intelligence in glaucoma: Connecting basic science with clinical applications

D Ma, LR Pasquale, MJA Girard, CKS Leung… - Frontiers in …, 2023 - frontiersin.org
Artificial intelligence (AI) has been approved for biomedical research in diverse areas from
bedside clinical studies to benchtop basic scientific research. For ophthalmic research, in …

Diffusion tensor imaging technology to quantitatively assess abnormal changes in patients with thyroid-associated ophthalmopathy

L Rui, L Jing, W Zhenchang - Frontiers in Human Neuroscience, 2022 - frontiersin.org
Objective We aim to investigate the feasibility of using diffusion tensor imaging (DTI) to
evaluate changes in extraocular muscles (EOMs) and lacrimal gland (LG) in patients with …

Thyroid-associated ophthalmopathy: Using diffusion tensor imaging to evaluate visual pathway microstructural changes

R Li, J Li, Z Wang - Frontiers in Neurology, 2022 - frontiersin.org
Objective The aim of this study was to determine whether the visual pathway is affected by
thyroid-associated ophthalmopathy (TAO) before the development of dysthyroid optic …

Unveiling Novel Structural Biomarkers for the Diagnosis of Glaucoma

YC Tsai, HP Lee, TH Tsung, YH Chen, DW Lu - Biomedicines, 2024 - mdpi.com
Glaucoma, a leading cause of irreversible blindness, poses a significant global health
burden. Early detection is crucial for effective management and prevention of vision loss …