Immune checkpoint inhibitors (ICIs) are a major class of immuno-oncology therapeutics that
have significantly improved the prognosis of various cancers, both in (neo) adjuvant and …

As the clinical applications of immune checkpoint inhibitors (ICIs) expand, our knowledge of
the potential adverse effects of these drugs continues to broaden. Emerging evidence …

ESC Guidelines e341 (1) the specific situation of the patient. In this respect, it is specified
that, unless otherwise provided for by national regulations, offlabel use of medication should …

Immune checkpoint inhibitors (ICI) have transformed the therapeutic landscape in oncology.
However, ICI can induce uncommon life-threatening autoimmune T-cell-mediated …

Immune checkpoint inhibitors (ICI) have known associations with cardiotoxicity. However, a
representative quantification of the adverse cardiovascular events and cardiovascular …

Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy by unleashing the
power of the immune system against malignant cells. However, their use is associated with a …

Background: Immune checkpoint inhibitors (ICIs) are becoming widely used for novel cancer
treatments. Immune-related adverse events, including cardiac toxicity, are frequently …

Simple Summary Myocarditis is an infrequent but highly hazardous complication of the
cancer therapy of immune checkpoint inhibitors (ICIs). The study of the pathophysiology of …

Advances in treatment, common cardiovascular (CV) risk factors and the ageing of the
population have led to an increasing number of cancer patients presenting with acute CV …

Objectives Knee osteoarthritis (KOA), a prevalent degenerative joint disease, is primarily
diagnosed through X-ray imaging. The Kellgren-Lawrence grading system (KL) is the gold …