The role of microRNAs in the pathophysiology of human central nervous system: a focus on neurodegenerative diseases

D Rezaee, F Saadatpour, N Akbari, A Zoghi… - Ageing research …, 2023 - Elsevier
Abstract microRNAs (miRNAs) are suggested to play substantial roles in regulating the
development and various physiologic functions of the central nervous system (CNS). These …

The kaleidoscope of microglial phenotypes

ML Dubbelaar, L Kracht, BJL Eggen… - Frontiers in …, 2018 - frontiersin.org
Gene expression analyses of microglia, the tissue-resident macrophages of the central
nervous system (CNS), led to the identification of homeostatic as well as neurological …

The role of exosomal microRNAs and oxidative stress in neurodegenerative diseases

X Wang, Y Zhou, Q Gao, D Ping, Y Wang… - Oxidative medicine …, 2020 - Wiley Online Library
Neurodegenerative diseases including Alzheimer's disease and Parkinson's disease are
aging‐associated diseases with irreversible damage of brain tissue. Oxidative stress is …

microRNAs in Parkinson's disease: from pathogenesis to novel diagnostic and therapeutic approaches

L Leggio, S Vivarelli, F L'Episcopo, C Tirolo… - International journal of …, 2017 - mdpi.com
Parkinson's disease (PD) is the most prevalent central nervous system (CNS) movement
disorder and the second most common neurodegenerative disease overall. PD is …

The role of noncoding RNAs in Parkinson's disease: biomarkers and associations with pathogenic pathways

MC Kuo, SCH Liu, YF Hsu, RM Wu - Journal of biomedical science, 2021 - Springer
The discovery of various noncoding RNAs (ncRNAs) and their biological implications is a
growing area in cell biology. Increasing evidence has revealed canonical and noncanonical …

The pervasive role of the miR-181 family in development, neurodegeneration, and cancer

A Indrieri, S Carrella, P Carotenuto, S Banfi… - International journal of …, 2020 - mdpi.com
MicroRNAs (miRNAs) are small noncoding RNAs playing a fundamental role in the
regulation of gene expression. Evidence accumulating in the past decades indicate that they …

Mitochondrial dysfunction and Parkinson's disease: pathogenesis and therapeutic strategies

S Moradi Vastegani, A Nasrolahi, S Ghaderi… - Neurochemical …, 2023 - Springer
Parkinson's disease (PD) is a common age-related neurodegenerative disorder whose
pathogenesis is not completely understood. Mitochondrial dysfunction and increased …

Role of MicroRNAs in Parkinson's disease

SY Goh, YX Chao, ST Dheen, EK Tan… - International journal of …, 2019 - mdpi.com
Parkinson's disease (PD) is a disabling neurodegenerative disease that manifests with
resting tremor, bradykinesia, rigidity and postural instability. Since the discovery of …

MicroRNA dysregulation in Parkinson's disease: a narrative review

YH Nies, NH Mohamad Najib, WL Lim… - Frontiers in …, 2021 - frontiersin.org
Parkinson's disease (PD) is a severely debilitating neurodegenerative disease, affecting the
motor system, leading to resting tremor, cogwheel rigidity, bradykinesia, walking and gait …

Small non-coding RNAs: new class of biomarkers and potential therapeutic targets in neurodegenerative disease

CN Watson, A Belli, V Di Pietro - Frontiers in genetics, 2019 - frontiersin.org
Neurodegenerative diseases (NDs) are becoming increasingly prevalent in the world, with
an aging population. In the last few decades, due to the devastating nature of these …