New insights into cerebrovascular pathophysiology and hypertension

AJS Webb, DJ Werring - Stroke, 2022 - Am Heart Assoc
Despite advances in acute management and prevention of cerebrovascular disease, stroke
and vascular cognitive impairment together remain the world's leading cause of death and …

Perinatal origins of adult disease and opportunities for health promotion: a narrative review

S Nobile, C Di Sipio Morgia, G Vento - Journal of Personalized Medicine, 2022 - mdpi.com
The “developmental origins of health and disease”(DOHaD) hypothesis refers to the
influence of early developmental exposures and fetal growth on the risk of chronic diseases …

[HTML][HTML] The heart in congenital diaphragmatic hernia: Knowns, unknowns, and future priorities

N Patel, AC Massolo, US Kraemer… - Frontiers in …, 2022 - frontiersin.org
There is growing recognition that the heart is a key contributor to the pathophysiology of
congenital diaphragmatic hernia, in conjunction with developmental abnormalities of the …

Birth weight influences cardiac structure, function, and disease risk: evidence of a causal association

M Ardissino, AP Morley, EAW Slob… - European heart …, 2024 - academic.oup.com
Abstract Background and Aims Low birth weight is a common pregnancy complication,
which has been associated with higher risk of cardiometabolic disease in later life. Prior …

Cardiac remodeling after hypertensive pregnancy following physician-optimized blood pressure self-management: the POP-HT randomized clinical trial imaging …

J Kitt, S Krasner, L Barr, A Frost, K Tucker… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: Hypertensive pregnancy disorders are associated with adverse cardiac
remodeling, which can fail to reverse in the postpartum period in some women. The …

Understanding the preterm human heart: What do we know so far?

A Schuermans, AJ Lewandowski - The Anatomical Record, 2022 - Wiley Online Library
Globally, preterm birth affects more than one in every 10 live births. Although the short‐term
cardiopulmonary complications of prematurity are well known, long‐term health effects are …

Intrauterine inflammation exacerbates maladaptive remodeling of the immature myocardium after preterm birth in lambs

A Vrselja, JJ Pillow, JG Bensley, SJ Ellery… - Pediatric …, 2022 - nature.com
Background Antenatal conditions that are linked with preterm birth, such as intrauterine
inflammation, can influence fetal cardiac development thereby rendering the heart more …

Birth weight is associated with clonal hematopoiesis of indeterminate potential and cardiovascular outcomes in adulthood

A Schuermans, T Nakao, Y Ruan… - Journal of the …, 2023 - Am Heart Assoc
Background High and low birth weight are independently associated with increased
cardiovascular disease risk in adulthood. Clonal hematopoiesis of indeterminate potential …

Lower birth weight is linked to poorer cardiovascular health in middle-aged population-based adults

Z Raisi-Estabragh, J Cooper, MS Bethell, C McCracken… - Heart, 2023 - heart.bmj.com
Objective To examine associations of birth weight with clinical and imaging indicators of
cardiovascular health and evaluate mechanistic pathways in the UK Biobank. Methods …

Acute and chronic cardiac adaptations in adults born preterm

AJ Lewandowski - Experimental Physiology, 2022 - Wiley Online Library
New Findings What is the topic of this review? Studies using cardiovascular magnetic
resonance imaging and echocardiography to investigate cardiac alterations at rest and …