Pathogenetic features and current management of glioblastoma

HM Nguyen, K Guz-Montgomery, DB Lowe, D Saha - Cancers, 2021 - mdpi.com
Simple Summary Glioblastoma (GBM) is the most common form of primary malignant brain
tumor with a devastatingly poor prognosis. Tumor heterogeneity (cellular, molecular and …

Understanding the glioblastoma tumor biology to optimize photodynamic therapy: From molecular to cellular events

LE Ibarra, ML Vilchez, MD Caverzán… - Journal of …, 2021 - Wiley Online Library
Photodynamic therapy (PDT) has recently gained attention as an alternative treatment of
malignant gliomas. Glioblastoma (GBM) is the most prevalent within tumors of the central …

Sonodynamic therapy in combination with photodynamic therapy shows enhanced long-term cure of brain tumor

BM Borah, J Cacaccio, FA Durrani, W Bshara… - Scientific Reports, 2020 - nature.com
This article presents the construction of a multimodality platform that can be used for efficient
destruction of brain tumor by a combination of photodynamic and sonodynamic therapy. For …

Preclinical studies with glioblastoma brain organoid co-cultures show efficient 5-ALA photodynamic therapy

L Pedrosa, C Bedia, D Diao, A Mosteiro, A Ferrés… - Cells, 2023 - mdpi.com
Background: The high recurrence of glioblastoma (GB) that occurs adjacent to the resection
cavity within two years of diagnosis urges an improvement of therapies oriented to GB local …

Low-level laser treatment induces the blood-brain barrier opening and the brain drainage system activation: delivery of liposomes into mouse glioblastoma

O Semyachkina-Glushkovskaya, D Bragin, O Bragina… - Pharmaceutics, 2023 - mdpi.com
The progress in brain diseases treatment is limited by the blood-brain barrier (BBB), which
prevents delivery of the vast majority of drugs from the blood into the brain. In this study, we …

Photodynamic therapy using a new folate receptor-targeted photosensitizer on peritoneal ovarian cancer cells induces the release of extracellular vesicles with …

M Baydoun, O Moralès, C Frochot, C Ludovic… - Journal of Clinical …, 2020 - mdpi.com
Often discovered at an advanced stage, ovarian cancer progresses to peritoneal carcinoma,
which corresponds to the invasion of the serosa by multiple tumor implants. The current …

ZC3H15 promotes glioblastoma progression through regulating EGFR stability

J Hou, M Xu, H Gu, D Pei, Y Liu, P Huang… - Cell death & …, 2022 - nature.com
Zinc finger CCCH-type containing 15 (ZC3H15), a highly conserved protein involved in
several cellular processes, which was responsible for tumorigenesis and may be a …

Enhanced delivery of rose Bengal by amino acids starvation and exosomes inhibition in human astrocytoma cells to potentiate anticancer photodynamic therapy …

B Slivinschi, F Manai, C Martinelli, F Carriero… - Cells, 2022 - mdpi.com
Photodynamic therapy (PDT) is a promising anticancer strategy based on the light energy
stimulation of photosensitizers (PS) molecules within a malignant cell. Among a multitude of …

Identification of dysregulated competing endogenous RNA networks in glioblastoma: A way toward improved therapeutic opportunities

S Rahnama, B Bakhshinejad, F Farzam, A Bitaraf… - Life Sciences, 2021 - Elsevier
Glioblastoma is recognized as one of the leading causes of death worldwide. Although there
have been considerable advancements in understanding the causative molecular …

[HTML][HTML] Multi-omics analysis predicts fibronectin 1 as a prognostic biomarker in glioblastoma multiforme

F Kabir, MNH Apu - Genomics, 2022 - Elsevier
Glioblastoma (GBM) is one of the most malignant and intractable central nervous system
tumors with high recurrence, low survival rate, and poor prognosis. Despite the advances of …