[HTML][HTML] CAR T cell-based immunotherapy for the treatment of glioblastoma
Glioblastoma multiforme (GBM) is the most common and aggressive malignant primary brain
tumor in adults. Current treatment options typically consist of surgery followed by …
tumor in adults. Current treatment options typically consist of surgery followed by …
Applications of radiomics and machine learning for radiotherapy of malignant brain tumors
M Kocher, MI Ruge, N Galldiks, P Lohmann - Strahlentherapie und …, 2020 - Springer
Background Magnetic resonance imaging (MRI) and amino acid positron-emission
tomography (PET) of the brain contain a vast amount of structural and functional information …
tomography (PET) of the brain contain a vast amount of structural and functional information …
Radiogenomic-based survival risk stratification of tumor habitat on Gd-T1w MRI is associated with biological processes in glioblastoma
Purpose: To (i) create a survival risk score using radiomic features from the tumor habitat on
routine MRI to predict progression-free survival (PFS) in glioblastoma and (ii) obtain a …
routine MRI to predict progression-free survival (PFS) in glioblastoma and (ii) obtain a …
LOX-1+ PMN-MDSC enhances immune suppression which promotes glioblastoma multiforme progression
EQ Chai, L Zhang, C Li - Cancer Management and Research, 2019 - Taylor & Francis
Background/aims Patients with glioblastoma multiforme (GBM) that is the most common
brain cancer in adults have a rather poor prognosis. The accumulation of immune …
brain cancer in adults have a rather poor prognosis. The accumulation of immune …
Scalp-sparing radiation with concurrent temozolomide and tumor treating fields (SPARE) for patients with newly diagnosed glioblastoma
Introduction Standard-of-care treatment for patients with newly diagnosed glioblastoma
(GBM) after surgery or biopsy includes concurrent chemoradiation followed by maintenance …
(GBM) after surgery or biopsy includes concurrent chemoradiation followed by maintenance …
Molecular characteristics and clinical features of multifocal glioblastoma
Abstract Introduction Glioblastomas (GBMs) usually occur as a solitary lesion; however,
about 0.5–35% present with multiple lesions (M-GBM). The genetic landscape of GBMs …
about 0.5–35% present with multiple lesions (M-GBM). The genetic landscape of GBMs …
TERT promoter mutation associated with multifocal phenotype and poor prognosis in patients with IDH wild-type glioblastoma
Z Kikuchi, I Shibahara, T Yamaki… - Neuro-Oncology …, 2020 - academic.oup.com
Background Although mutations in the promoter region of the telomerase reverse
transcriptase (TERT p) gene are the most common alterations in glioblastoma (GBM), their …
transcriptase (TERT p) gene are the most common alterations in glioblastoma (GBM), their …
Multifocal high-grade glioma radiotherapy safety and efficacy
DF Fleischmann, R Schön, S Corradini… - Radiation …, 2021 - Springer
Background Multifocal manifestation of high-grade glioma is a rare disease with very
unfavourable prognosis. The pathogenesis of multifocal glioma and pathophysiological …
unfavourable prognosis. The pathogenesis of multifocal glioma and pathophysiological …
Patterns of management and outcomes of unifocal versus multifocal glioblastoma
W Haque, Y Thong, V Verma, R Rostomily… - Journal of Clinical …, 2020 - Elsevier
Background Glioblastoma (GBM) presents as a solitary lesion (unifocal), or as multiple
discrete lesions (multifocal). Multifocal GBM may have a worse prognosis as compared to …
discrete lesions (multifocal). Multifocal GBM may have a worse prognosis as compared to …
Predicting glioblastoma recurrence from preoperative MR scans using fractional-anisotropy maps with free-water suppression
Diffusion tensor imaging (DTI), and fractional-anisotropy (FA) maps in particular, have
shown promise in predicting areas of tumor recurrence in glioblastoma. However, analysis …
shown promise in predicting areas of tumor recurrence in glioblastoma. However, analysis …