The limited armamentarium against drug-resistant Gram-negative bacilli has led to the
development of several novel β-lactam–β-lactamase inhibitor combinations (BLBLIs). In this …

SUMMARY β-Lactam antibiotics have been widely used as therapeutic agents for the past
70 years, resulting in emergence of an abundance of β-lactam-inactivating β-lactamases …

Carbapenemases are β-lactamases belonging to different Ambler classes (A, B, D) and can
be encoded by both chromosomal and plasmid-mediated genes. These enzymes represent …

ABSTRACT A greater ethical conscience, new global rules and a modified perception of
ethical consciousness entail a more rigorous control on utilizations of vertebrates for in vivo …

These updated guidelines from the Infectious Diseases Community of Practice of the
American Society of Transplantation review the diagnosis, prevention, and management of …

Burkholderia cepacia complex (Bcc) is an emerging pathogen causes life-threatening
infections in cystic fibrosis patients. This narrative review aims to highlight an update on the …

ABSTRACT Introduction: Non-fermenting Gram-negative bacilli are at the center of the
antimicrobial resistance epidemic. Acinetobacter baumannii and Pseudomonas aeruginosa …

Ventilator-associated pneumonia (VAP) in critically ill patients with COVID-19 represents a
very huge global threat due to a higher incidence rate compared to non-COVID-19 patients …

Purpose Ceftazidime–avibactam is an antimicrobial association active against several
Enterobacteriaceae species, including those resistant to carbapenem. Considering the …

Abstract Background Burkholderia cepacia complex (Bc c) are a group of multidrug-resistant
gram-negative bacteria rarely reported in patients without cystic fibrosis (CF) or …