Typical bioprocess comprises of different unit operations wherein a near optimal
environment is required for cells to grow, divide, and synthesize the desired product …

A majority of industrial fermentation processes are operated in fed-batch mode. In this case,
the rate of feed addition to the system is a focus for optimising the process operation, as it …

A future-oriented approach is the application of Digital Twins for process development,
optimization and finally during manufacturing. Digital Twins are detailed virtual …

This paper proposes an enhanced model predictive control (MPC) using a new state space
structure for temperature control of an industrial coke furnace. The advantage of the …

To harness energy security and reduce carbon emissions, humankind is trying to switch
toward renewable energy resources. To this extent, fatty acid methyl esters, also known as …

In this paper, the control problem for continuously stirred tank reactor (CSTR) systems with
input nonlinearities and unknown disturbances is addressed. To ensure constraints …

This article discusses the problem of nonuniform running length in incomplete tracking
control, which often occurs in industrial processes due to artificial or environmental changes …

This article presents an improved batch-to-batch optimisation technique that is shown to be
able to bring the yield closer to its set-point from one batch to the next. In addition, an …

In continuous pharmaceutical manufacturing, real-time precise control of critical quality
attributes (CQAs) is necessary for quality by design (QbD)-based manufacturing and real …

To address the challenge of linear quadratic tracking for batch processes without taking into
account the specifics regarding the system dynamics and the state observer, a two …