EP Gillis, KJ Eastman, MD Hill… - Journal of medicinal …, 2015 - ACS Publications
The role of fluorine in drug design and development is expanding rapidly as we learn more about the unique properties associated with this unusual element and how to deploy it with …
P Long, Y Feng, C Cao, Y Li, J Han, S Li… - Advanced Functional …, 2018 - Wiley Online Library
The unstable triplet excited state is a core problem when developing self‐protective room temperature phosphorescence (RTP) in carbon dots (CDs). Here, fluorine and nitrogen …
S Preshlock, M Tredwell, V Gouverneur - Chemical reviews, 2016 - ACS Publications
Diverse radiochemistry is an essential component of nuclear medicine; this includes imaging techniques such as positron emission tomography (PET). As such, PET can track …
Taking into account the vast arrays of fluorinated motifs known, 11 this review will be limited to the monofluorination of organic compounds, ie, synthetic methods allowing the …
S Ali, J Zhou - European journal of medicinal chemistry, 2023 - Elsevier
The objective of this review is to provide an update on the fluorine-containing drugs approved by US Food and Drug Administration in the span of past five years (2018–2022) …
T Liang, CN Neumann, T Ritter - … Chemie International Edition, 2013 - Wiley Online Library
Over the past decade, the most significant, conceptual advances in the field of fluorination were enabled most prominently by organo‐and transition‐metal catalysis. The most …
X Deng, J Rong, L Wang, N Vasdev… - Angewandte Chemie …, 2019 - Wiley Online Library
Positron emission tomography (PET) is a molecular imaging technology that provides quantitative information about function and metabolism in biological processes in vivo for …
MG Campbell, T Ritter - Chemical Reviews, 2015 - ACS Publications
In recent years, there has been a dramatic increase in available methods for the installation of fluorine and fluorine-containing functional groups in organic molecules, 1− 4 and the …
O Jacobson, DO Kiesewetter, X Chen - Bioconjugate chemistry, 2015 - ACS Publications
Fluorine-18 is the most frequently used radioisotope in positron emission tomography (PET) radiopharmaceuticals in both clinical and preclinical research. Its physical and nuclear …