Therapeutic targeting of noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and
long noncoding RNAs (lncRNAs), represents an attractive approach for the treatment of …

MicroRNAs (miRNAs) are pervasively expressed and regulate most biological functions.
They function by modulating transcriptional and translational programs and therefore they …

MicroRNAs (miRNAs) have recently emerged as key regulators of metabolism. For example,
miR-33a and miR-33b have a crucial role in controlling cholesterol and lipid metabolism in …

Small, noncoding microRNAs (miRNAs) regulate diverse biological functions in the liver and
increasing evidence suggests that they have a role in liver pathology. This Review …

The discovery of hepatitis C virus (HCV) in 1989 permitted basic research to unravel critical
components of a complex life cycle for this important human pathogen. HCV is a highly …

MicroRNAs are small non‐coding RNA guide molecules that regulate gene expression via
association with effector complexes and sequence‐specific recognition of target sites on …

Rationale: Tailored inflammation control is badly needed for the treatment of kinds of
inflammatory diseases, such as atherosclerosis. IL-10 is a potent anti-inflammatory cytokine …

MicroRNAs (miRNAs) are short noncoding RNAs, which bind to messenger RNAs and
regulate protein expression. The biosynthesis of miRNAs includes two precursors, a primary …

microRNA-122 (miR-122) was one of the first examples of a tissue-specific miRNA. It is
highly expressed in liver, where it constitutes 70% of the total miRNA pool. miR-122 …

MicroRNAs (miRNAs) are small noncoding RNAs that regulate eukaryotic gene expression
by binding to regions of imperfect complementarity in mRNAs, typically in the 3′ UTR …