Peripheral nerve injuries (PNI) occur as the result of sudden trauma and can lead to life-long
disability, reduced quality of life, and heavy economic and social burdens. Although the …

Biomaterials are essential for the development of innovative biomedical and therapeutic
applications. Biomaterials‐based scaffolds can influence directed cell differentiation to …

In this study, gelatin-based 3D conduits with three different microstructures (nanofibrous,
macroporous and ladder-like) were fabricated for the first time via combined molding and …

The use of genetically modified mesenchymal stem cells (MSCs) is a rapidly growing area of
research targeting delivery of therapeutic factors for neuro-repair. Cells can be programmed …

While transplantation of Schwann cells facilitates axon regeneration, remyelination and
repair after peripheral nerve injury clinical use is limited by cell bioavailability. We posit that …

Abstract: A fundamental issue in biology concerns how cells establish and maintain their
identity during early embryogenesis. Gaining a better understanding of these rules is key to …

This study investigated the effect of electrical stimuli parameters using graphene-based
devices for the transdifferentiation of genetically engineered brain-derived neurotrophic …

Provided herein are methods and compositions for dynamically controlling and targeting
multiple immunosuppressive mechanisms in cancer. Some aspects provide cells …

Xu et al.“Bone marrow-derived mesenchymal stem cells co expressing interleukin-18 and
interferon-ß exhibit potent antitumor effect against intracranial glioma in rats." Oncol Rep …

Provided herein are methods and compositions for dynamically controlling and targeting
multiple immunosuppressive mechanisms in cancer. Some aspects provide cells …