The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical
application in a rational manner depends on reliable, clinically applicable methods for …

Work over several decades has laid solid foundations for the advancement of liver cell
therapy. To date liver cell therapy in people has taken the form of hepatocyte transplantation …

Liver transplantation is the accepted treatment for patients with acute liver failure and liver-
based metabolic disorders. However, donor organ shortage and lifelong need for …

Hepatocyte transplantation has shown potential as an additional treatment modality for
certain diseases of the liver. To date, patients with liver-based metabolic disorders or acute …

Background—Transplantation of endothelial progenitor cells (EPCs) improves
vascularization and left ventricular function after experimental myocardial ischemia …

Hepatocyte transplantation (HT) has been performed in patients with liver-based metabolic
disease and acute liver failure as a potential alternative to liver transplantation. The results …

On September 6 and 7, 2009 a meeting was held in London to identify and discuss what are
perceived to be current roadblocks to effective hepatocyte transplantation as it is currently …

Transplantation of progenitor cells (PCs) has been shown to improve neovascularization
and left ventricular function after myocardial ischemia. The fate of transplanted PCs has …

Since the first human hepatocyte transplants (HTx) in 1992, clinical studies have clearly
established proof of principle for this therapy as a treatment for patients with acquired or …

Inherited metabolic diseases of the liver are characterized by deficiency of a hepatic enzyme
or protein often resulting in life‐threatening disease. The remaining liver function is usually …