Perturbations of native membrane protein structure in alkyl phosphocholine detergents: a critical assessment of NMR and biophysical studies

C Chipot, F Dehez, JR Schnell, N Zitzmann… - Chemical …, 2018 - ACS Publications
Membrane proteins perform a host of vital cellular functions. Deciphering the molecular
mechanisms whereby they fulfill these functions requires detailed biophysical and structural …

Towards a true protein movie: a perspective on the potential impact of the ensemble-based structure determination using exact NOEs

B Vögeli, J Orts, D Strotz, C Chi, M Minges… - Journal of magnetic …, 2014 - Elsevier
Confined by the Boltzmann distribution of the energies of the states, a multitude of structural
states are inherent to biomolecules. For a detailed understanding of a protein's function, its …

Backbone and methyl assignment of bacteriorhodopsin incorporated into nanodiscs

L Kooijman, P Ansorge, M Schuster… - Journal of biomolecular …, 2020 - Springer
Resonance assignments are challenging for membrane proteins due to the size of the
lipid/detergent-protein complex and the presence of line-broadening from conformational …

Membrane fusion and infection of the influenza hemagglutinin

ST Smrt, JL Lorieau - Protein Reviews: Volume 18, 2017 - Springer
The influenza virus is a major health concern associated with an estimated 5000 to 30,000
deaths every year (Reed et al. 2015) and a significant economic impact with the …

Direct evaluation of protein–lipid contacts reveals protein membrane immersion and isotropic bicelle structure

T Schmidt, AJ Situ, TS Ulmer - The journal of physical chemistry …, 2016 - ACS Publications
The solvation of membrane proteins by both lipids and water makes their membrane
immersion difficult to predict and the choice of a membrane mimic challenging. To …

[HTML][HTML] The nuclear Overhauser Effect (NOE) as a tool to study macromolecular confinement: Elucidation and disentangling of crowding and encapsulation effects

P Honegger, O Steinhauser - The Journal of Chemical Physics, 2020 - pubs.aip.org
We propose a methodology to capture short-lived but biophysically important contacts of
biomacromolecules using the biomolecule-water nuclear Overhauser effect as an indirect …

[PDF][PDF] Peptide-Based Strategies of Delivering Semiconductor Nanocrystals into Living Cells

CIR Vera - 2017 - indigo.uic.edu
Semiconductor nanocrystals or quantum dots (QDs) possess exceptional optical and
physicochemical properties, for instance, their brightness and long fluorescence lifetimes …

Structural and Functional Study of Viral Membrane Proteins in Solution State NMR

MA Ayhan - 2022 - search.proquest.com
The recent occurrence of the SARS-CoV2 virus, causing COVID-19, has shown that we still
do not have sufficient knowledge of the infection mechanism of such human infecting viruses …