Quercetin: its main pharmacological activity and potential application in clinical medicine

D Yang, T Wang, M Long, P Li - Oxidative Medicine and …, 2020 - Wiley Online Library
Quercetin is a flavonoid compound widely present in plants and exhibits a variety of
biological activities. Research on quercetin has shown its potential for medical application …

The anti-cancer effect of quercetin: molecular implications in cancer metabolism

M Reyes-Farias, C Carrasco-Pozo - International journal of molecular …, 2019 - mdpi.com
Cancer is a problem with worldwide importance and is the second leading cause of death
globally. Cancer cells reprogram their metabolism to support their uncontrolled expansion …

Healthy effects of plant polyphenols: molecular mechanisms

M Leri, M Scuto, ML Ontario, V Calabrese… - International journal of …, 2020 - mdpi.com
The increasing extension in life expectancy of human beings in developed countries is
accompanied by a progressively greater rate of degenerative diseases associated with …

Flavonoids in cancer and apoptosis

M Abotaleb, SM Samuel, E Varghese, S Varghese… - Cancers, 2018 - mdpi.com
Cancer is the second leading cause of death globally. Although, there are many different
approaches to cancer treatment, they are often painful due to adverse side effects and are …

A comprehensive analysis and anti-cancer activities of quercetin in ROS-mediated cancer and cancer stem cells

P Biswas, D Dey, PK Biswas, TI Rahaman… - International journal of …, 2022 - mdpi.com
Reactive oxygen species (ROS) induce carcinogenesis by causing genetic mutations,
activating oncogenes, and increasing oxidative stress, all of which affect cell proliferation …

Targeting autophagy, oxidative stress, and ER stress for neurodegenerative disease treatment

Y Esmaeili, Z Yarjanli, F Pakniya, E Bidram… - Journal of Controlled …, 2022 - Elsevier
Protein homeostasis is a vital process for cell function and, therefore, disruption of the
molecular mechanisms involved in this process, such as autophagy, may contribute to …

Quercetin and cancer: new insights into its therapeutic effects on ovarian cancer cells

A Vafadar, Z Shabaninejad, A Movahedpour, F Fallahi… - Cell & bioscience, 2020 - Springer
Ovarian cancer is known as a serious malignancy that affects women's reproductive tract
and can considerably threat their health. A wide range of molecular mechanisms and …

Crosstalk between autophagy and epithelial-mesenchymal transition and its application in cancer therapy

HT Chen, H Liu, MJ Mao, Y Tan, XQ Mo, XJ Meng… - Molecular cancer, 2019 - Springer
Autophagy is a highly conserved catabolic process that mediates degradation of pernicious
or dysfunctional cellular components, such as invasive pathogens, senescent proteins, and …

Potential therapeutic targets of quercetin, a plant flavonol, and its role in the therapy of various types of cancer through the modulation of various cell signaling …

SA Almatroodi, MA Alsahli, A Almatroudi, AK Verma… - Molecules, 2021 - mdpi.com
Polyphenolic flavonoids are considered natural, non-toxic chemopreventers, which are most
commonly derived from plants, fruits, and vegetables. Most of these polyphenolics exhibit …

[HTML][HTML] Functions of polyphenols and its anticancer properties in biomedical research: a narrative review

PB Bhosale, SE Ha, P Vetrivel, HH Kim… - Translational cancer …, 2020 - ncbi.nlm.nih.gov
Cancer is a major health concern as the incidence is growing worldwide and still lacks
successful therapies. Plant-derived functional foods are getting considerable attention …