The role of transient receptor potential cation channels in Ca2+ signaling
M Gees, B Colsoul, B Nilius - Cold Spring Harbor …, 2010 - cshperspectives.cshlp.org
The 28 mammalian members of the super-family of transient receptor potential (TRP)
channels are cation channels, mostly permeable to both monovalent and divalent cations …
channels are cation channels, mostly permeable to both monovalent and divalent cations …
TRPM family channels in cancer
A Hantute-Ghesquier, A Haustrate, N Prevarskaya… - Pharmaceuticals, 2018 - mdpi.com
Members of the TRPM (“Melastatin”) family fall into the subclass of the TRP channels having
varying permeability to Ca2+ and Mg2+, with three members of the TRPM family being …
varying permeability to Ca2+ and Mg2+, with three members of the TRPM family being …
Structural mechanisms of TRPM7 activation and inhibition
KD Nadezhdin, L Correia, C Narangoda… - Nature …, 2023 - nature.com
The transient receptor potential channel TRPM7 is a master regulator of the organismal
balance of divalent cations that plays an essential role in embryonic development, immune …
balance of divalent cations that plays an essential role in embryonic development, immune …
Comparative genomic analyses reveal a vast, novel network of nucleotide-centric systems in biological conflicts, immunity and signaling
AM Burroughs, D Zhang, DE Schäffer… - Nucleic acids …, 2015 - academic.oup.com
Cyclic di-and linear oligo-nucleotide signals activate defenses against invasive nucleic
acids in animal immunity; however, their evolutionary antecedents are poorly understood …
acids in animal immunity; however, their evolutionary antecedents are poorly understood …
The molecular appearance of native TRPM7 channel complexes identified by high-resolution proteomics
A Kollewe, V Chubanov, FT Tseung, L Correia… - Elife, 2021 - elifesciences.org
The transient receptor potential melastatin-subfamily member 7 (TRPM7) is a ubiquitously
expressed membrane protein consisting of ion channel and protein kinase domains. TRPM7 …
expressed membrane protein consisting of ion channel and protein kinase domains. TRPM7 …
TRPM channels in human diseases
The transient receptor potential melastatin (TRPM) subfamily belongs to the TRP cation
channels family. Since the first cloning of TRPM1 in 1989, tremendous progress has been …
channels family. Since the first cloning of TRPM1 in 1989, tremendous progress has been …
The TRPM2 ion channel, an oxidative stress and metabolic sensor regulating innate immunity and inflammation
H Knowles, Y Li, AL Perraud - Immunologic research, 2013 - Springer
TRPM2 (transient receptor potential melastatin 2) is the unique fusion of a Ca 2+-permeable
pore with an enzymatic domain that binds the NAD+-metabolite ADP-ribose (ADPR) …
pore with an enzymatic domain that binds the NAD+-metabolite ADP-ribose (ADPR) …
Natural and synthetic modulators of SK (Kca2) potassium channels inhibit magnesium‐dependent activity of the kinase‐coupled cation channel TRPM7
V Chubanov, M Mederos y Schnitzler… - British journal of …, 2012 - Wiley Online Library
BACKGROUND AND PURPOSE Transient receptor potential cation channel subfamily M
member 7 (TRPM7) is a bifunctional protein comprising a TRP ion channel segment linked …
member 7 (TRPM7) is a bifunctional protein comprising a TRP ion channel segment linked …
Permeation, regulation and control of expression of TRP channels by trace metal ions
A Bouron, K Kiselyov, J Oberwinkler - Pflügers Archiv-European Journal of …, 2015 - Springer
Transient receptor potential (TRP) channels form a diverse family of cation channels
comprising 28 members in mammals. Although some TRP proteins can only be found on …
comprising 28 members in mammals. Although some TRP proteins can only be found on …
Trpm7
A Fleig, V Chubanov - … Receptor Potential (TRP) Cation Channels: Volume …, 2014 - Springer
The channel kinases TRPM6 and TRPM7 are fusion proteins with an ion transport domain
and an enzymatically active kinase domain. TRPM7 has been found in every mammalian …
and an enzymatically active kinase domain. TRPM7 has been found in every mammalian …