The Multiple Sclerosis Functional Composite measure (MSFC): an integrated approach to MS clinical outcome assessment

JS Fischer, RA Rudick, GR Cutter… - Multiple Sclerosis …, 1999 - journals.sagepub.com
Clinical outcome assessment in Multiple Sclerosis (MS) is challenging due to the diversity
and fluctuating nature of MS symptoms. Traditional clinical scales such as the EDSS are …

The multiple sclerosis functional composite: a new clinical outcome measure for multiple sclerosis trials

RA Rudick, G Cutter, S Reingold - Multiple Sclerosis Journal, 2002 - journals.sagepub.com
With the advent and widespread use of partially effective disease modifying drug therapies
for multiple sclerosis (MS), future clinical trials will undoubtedly test experimental …

[HTML][HTML] A prospective open-label study of endovascular treatment of chronic cerebrospinal venous insufficiency

P Zamboni, R Galeotti, E Menegatti… - Journal of vascular …, 2009 - Elsevier
OBJECTIVE: Chronic cerebrospinal venous insufficiency (CCSVI) is characterized by
combined stenoses of the principal pathways of extracranial venous drainage, including the …

Benefit of interferon β-1a on MSFC progression in secondary progressive MS

JA Cohen, GR Cutter, JS Fischer, AD Goodman… - Neurology, 2002 - AAN Enterprises
Background: Interferon β-1a (IFNβ-1a, Avonex) is efficacious in relapsing forms of MS.
Studies of other IFNβ preparations in secondary progressive MS (SPMS) yielded conflicting …

Brain metabolite changes in cortical grey and normal‐appearing white matter in clinically early relapsing–remitting multiple sclerosis

DT Chard, CM Griffin, MA McLean, P Kapeller… - Brain, 2002 - academic.oup.com
While much work has concentrated on focal white matter (WM) lesions in multiple sclerosis,
there is growing evidence to suggest that normal‐appearing WM (NAWM) and grey matter …

Randomized controlled trial of an energy conservation course for persons with multiple sclerosis

VG Mathiowetz, ML Finlayson… - Multiple Sclerosis …, 2005 - journals.sagepub.com
Objective: To assess the short-term efficacy and effectiveness of a six-week energy
conservation course on fatigue impact, quality of life and self-efficacy for persons with …

Long–term exercise improves functional impairment but not quality of life in multiple sclerosis

A Romberg, A Virtanen, J Ruutiainen - Journal of neurology, 2005 - Springer
Regular exercise is important for patients with multiple sclerosis (MS) to maintain their
functional ability and general health. The aim of this study was to determine whether a long …

Cognitive functioning in children and adolescents with multiple sclerosis

WS MacAllister, AL Belman, M Milazzo, DM Weisbrot… - Neurology, 2005 - AAN Enterprises
Objective: To examine cognitive functioning in children with multiple sclerosis (MS).
Methods: The authors examined the neuropsychological profile of 37 children with a …

Participation restriction in people with multiple sclerosis: prevalence and correlations with cognitive, walking, balance, and upper limb impairments

D Cattaneo, I Lamers, R Bertoni, P Feys… - Archives of physical …, 2017 - Elsevier
Objectives To calculate the percentage of participation restrictions according to disability
level in multiple sclerosis (MS), and to assess the relationship between participation …

Treatment with laquinimod reduces development of active MRI lesions in relapsing MS

C Polman, F Barkhof, M Sandberg-Wollheim, A Linde… - Neurology, 2005 - AAN Enterprises
Background: Laquinimod is a novel immunomodulatory substance developed as an orally
available disease modifying treatment in multiple sclerosis (MS). The purpose of this study …