Radiation: a poly-traumatic hit leading to multi-organ injury

JG Kiang, AO Olabisi - Cell & bioscience, 2019 - Springer
The range of radiation threats we face today includes everything from individual radiation
exposures to mass casualties resulting from a terrorist incident, and many of these exposure …

Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo

KS Schluns, WC Kieper, SC Jameson… - Nature immunology, 2000 - nature.com
The naïve and memory T lymphocyte pools are maintained through poorly understood
homeostatic mechanisms that may include signaling via cytokine receptors. We show that …

Protective effects of oridonin against osteoporosis by regulating immunity and activating the Wnt3a/β-catenin/VEGF pathway in ovariectomized mice

F Yu, J Chang, J Li, Z Li, H Zhang, Q Liu - International …, 2023 - Elsevier
This study was performed with the aim of investigating the effect of oridonin (ORI) on
estrogen deprivation-induced osteoporosis in mice and its mechanism. Animal experiments …

FcγRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection

A Ioan-Facsinay, SJ De Kimpe, SMM Hellwig… - Immunity, 2002 - cell.com
The high-affinity receptor for IgG, FcγRI, shares its capacity to bind IgG2a immune
complexes (IgG2a-IC) with the low-affinity receptor FcγRIII and complement factors …

Fatigue, serum cytokine levels, and blood cell counts during radiotherapy of patients with breast cancer

H Geinitz, FB Zimmermann, P Stoll, R Thamm… - International Journal of …, 2001 - Elsevier
Purpose: To assess the level of fatigue during the course of adjuvant radiotherapy (RT) of
breast cancer patients and its relation to anxiety, depression, serum cytokines, and blood …

Androstenediol stimulates myelopoiesis and enhances resistance to infection in gamma-irradiated mice

MH Whitnall, TB Elliott, RA Harding, CE Inal… - International journal of …, 2000 - Elsevier
The ionizing radiation-induced hemopoietic syndrome is characterized by defects in immune
function and increased mortality due to infections and hemorrhage. Since the steroid 5 …

Wound trauma increases radiation-induced mortality by activation of iNOS pathway and elevation of cytokine concentrations and bacterial infection

JG Kiang, W Jiao, LH Cary, SR Mog… - Radiation …, 2010 - meridian.allenpress.com
Although it is documented that concurrent wounding increases mortality from radiation
injury, the molecular mechanism of combined injury is unknown. In this study, mice were …

Pulmonary and hepatic gene expression following cecal ligation and puncture: monophosphoryl lipid A prophylaxis attenuates sepsis-induced cytokine and …

CA Salkowski, G Detore, A Franks, MC Falk… - Infection and …, 1998 - Am Soc Microbiol
Polymicrobial sepsis induced by cecal ligation and puncture (CLP) reproduces many of the
pathophysiologic features of septic shock. In this study, we demonstrate that mRNA for a …

Effects of calorie restriction on polymicrobial peritonitis induced by cecum ligation and puncture in young C57BL/6 mice

D Sun, AR Muthukumar, RA Lawrence… - Clinical Diagnostic …, 2001 - Am Soc Microbiol
Calorie restriction (CR) is known to prolong the life span and maintain an active immune
function in aged mice, but it is still not known if rodents under CR can respond optimally to …

Dietary antioxidants protect hematopoietic cells and improve animal survival after total-body irradiation

C Wambi, J Sanzari, XS Wan, M Nuth… - Radiation …, 2008 - meridian.allenpress.com
Abstract Wambi, C., Sanzari, J., Wan, XS, Nuth, M., Davis, J., Ko, YH, Sayers, CM, Baran, M.,
Ware, JH and Kennedy, AR Dietary Antioxidants Protect Hematopoietic Cells and Improve …