Sepsis is the life-threatening organ dysfunction caused by a dysregulated host response to
infection and is the leading cause of death in intensive care units. Cardiac dysfunction …

A close and intriguing relationship has been suggested between heart failure (HF) and
coronavirus disease 2019 (COVID-19). First, COVID-19 pandemic represented a global …

Abstract Aims Coronavirus disease 2019 (COVID-19) due to severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) has been associated with cardiovascular features of …

Objectives: To describe, with an emphasis on clinical applications, what is known about the
pathophysiology, management, and implications of septic cardiomyopathy in the adult ICU …

Background Growing evidence associates organ dysfunction (s) with impaired metabolism
in sepsis. Recent research has increased our understanding of the role of substrate …

Sepsis is a highly lethal and urgent unmet medical need. It is the result of a complex
interplay of several pathways, including inflammation, immune activation, hypoxia, and …

Sepsis is defined as “life-threatening organ dysfunction caused by a dysregulated host
response to infection”. Contrary to the older definitions, the current one not only focuses on …

Septic shock, the most severe complication of sepsis, accounts for∼ 10% of all admissions
to intensive care. Our understanding of its complex pathophysiology remains incomplete but …

Objectives: To review mechanisms underlying sepsis-induced cardiac dysfunction in
general and intrinsic myocardial depression in particular. Data Source: MEDLINE database …

Myocardial dysfunction is one of the main predictors of poor outcome in septic patients, with
mortality rates next to 70%. During the sepsis-induced myocardial dysfunction, both …