[HTML][HTML] TFMLAB: A MATLAB toolbox for 4D traction force microscopy

J Barrasa-Fano, A Shapeti, A Jorge-Penas… - SoftwareX, 2021 - Elsevier
We present TFMLAB, a MATLAB software package for 4D (x; y; z; t) Traction Force
Microscopy (TFM). While various TFM computational workflows are available in the …

Nonlinear Elastic Bottlebrush Polymer Hydrogels Modulate Actomyosin Mediated Protrusion Formation in Mesenchymal Stromal Cells

ML Ohnsorg, KM Mash, A Khang, VV Rao… - Advanced …, 2024 - Wiley Online Library
The nonlinear elasticity of many tissue‐specific extracellular matrices is difficult to
recapitulate without the use of fibrous architectures, which couple strain‐stiffening with …

Sarc-Graph: Automated segmentation, tracking, and analysis of sarcomeres in hiPSC-derived cardiomyocytes

B Zhao, K Zhang, CS Chen… - PLoS computational …, 2021 - journals.plos.org
A better fundamental understanding of human induced pluripotent stem cell-derived
cardiomyocytes (hiPSC-CMs) has the potential to advance applications ranging from drug …

Three-dimensional analysis of hydrogel-imbedded aortic valve interstitial cell shape and its relation to contractile behavior

A Khang, Q Nguyen, X Feng, DP Howsmon, MS Sacks - Acta biomaterialia, 2023 - Elsevier
Cell-shape is a conglomerate of mechanical, chemical, and biological mechanisms that
reflects the cell biophysical state. In a specific application, we consider aortic valve interstitial …

[HTML][HTML] Functional differences in human aortic valve interstitial cells from patients with varying calcific aortic valve disease

R Tuscher, A Khang, TM West, C Camillo… - Frontiers in …, 2023 - frontiersin.org
Calcific aortic valve disease (CAVD) is characterized by progressive stiffening of aortic valve
(AV) tissues, inducing stenosis and insufficiency. Bicuspid aortic valve (BAV) is a common …

SerialTrack: ScalE and rotation invariant augmented Lagrangian particle tracking

J Yang, Y Yin, AK Landauer, S Buyukozturk, J Zhang… - SoftwareX, 2022 - Elsevier
We present a new particle tracking algorithm for accurately resolving large deformation and
rotational motion fields, which takes advantage of both local and global particle tracking …

Dual-frame Fluid Motion Estimation with Test-time Optimization and Zero-divergence Loss

Y Zhang, H Gao, Z Jiang, H Zhao - arXiv preprint arXiv:2410.11934, 2024 - arxiv.org
3D particle tracking velocimetry (PTV) is a key technique for analyzing turbulent flow, one of
the most challenging computational problems of our century. At the core of 3D PTV is the …

Estimation of aortic valve interstitial cell-induced 3D remodeling of poly (ethylene glycol) hydrogel environments using an inverse finite element approach

A Khang, J Steinman, R Tuscher, X Feng, MS Sacks - Acta Biomaterialia, 2023 - Elsevier
Aortic valve interstitial cells (AVICs) reside within the leaflet tissues of the aortic valve and
maintain and remodel its extracellular matrix components. Part of this process is a result of …

An Inverse Modeling Approach to Estimate Three-Dimensional Aortic Valve Interstitial Cell Stress Fiber Force Levels

A Khang, K Meyer, MS Sacks - Journal of …, 2023 - asmedigitalcollection.asme.org
Within the aortic valve (AV) leaflet exists a population of interstitial cells (AVICs) that
maintain the constituent tissues by extracellular matrix (ECM) secretion, degradation, and …

On the three-dimensional correlation between myofibroblast shape and contraction

A Khang, E Lejeune… - Journal of …, 2021 - asmedigitalcollection.asme.org
Myofibroblasts are responsible for wound healing and tissue repair across all organ
systems. In periods of growth and disease, myofibroblasts can undergo a phenotypic …