The nonlinear elasticity of many tissue‐specific extracellular matrices is difficult to recapitulate without the use of fibrous architectures, which couple strain‐stiffening with …
B Zhao, K Zhang, CS Chen… - PLoS computational …, 2021 - journals.plos.org
A better fundamental understanding of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) has the potential to advance applications ranging from drug …
Cell-shape is a conglomerate of mechanical, chemical, and biological mechanisms that reflects the cell biophysical state. In a specific application, we consider aortic valve interstitial …
Calcific aortic valve disease (CAVD) is characterized by progressive stiffening of aortic valve (AV) tissues, inducing stenosis and insufficiency. Bicuspid aortic valve (BAV) is a common …
We present a new particle tracking algorithm for accurately resolving large deformation and rotational motion fields, which takes advantage of both local and global particle tracking …
Y Zhang, H Gao, Z Jiang, H Zhao - arXiv preprint arXiv:2410.11934, 2024 - arxiv.org
3D particle tracking velocimetry (PTV) is a key technique for analyzing turbulent flow, one of the most challenging computational problems of our century. At the core of 3D PTV is the …
Aortic valve interstitial cells (AVICs) reside within the leaflet tissues of the aortic valve and maintain and remodel its extracellular matrix components. Part of this process is a result of …
Within the aortic valve (AV) leaflet exists a population of interstitial cells (AVICs) that maintain the constituent tissues by extracellular matrix (ECM) secretion, degradation, and …
A Khang, E Lejeune… - Journal of …, 2021 - asmedigitalcollection.asme.org
Myofibroblasts are responsible for wound healing and tissue repair across all organ systems. In periods of growth and disease, myofibroblasts can undergo a phenotypic …