Benzodiazepines in the management of seizures and status epilepticus: a review of routes of delivery, pharmacokinetics, efficacy, and tolerability
R Kienitz, L Kay, I Beuchat, S Gelhard… - CNS drugs, 2022 - Springer
Status epilepticus (SE) is an acute, life-threatening medical condition that requires
immediate, effective therapy. Therefore, the acute care of prolonged seizures and SE is a …
immediate, effective therapy. Therefore, the acute care of prolonged seizures and SE is a …
[HTML][HTML] Febrile seizures: an overview
AKC Leung, KL Hon, TNH Leung - Drugs in context, 2018 - ncbi.nlm.nih.gov
Febrile seizures: an overview - PMC Back to Top Skip to main content NIH NLM Logo Access
keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation Preview …
keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation Preview …
[HTML][HTML] Randomized trial of three anticonvulsant medications for status epilepticus
Background The choice of drugs for patients with status epilepticus that is refractory to
treatment with benzodiazepines has not been thoroughly studied. Methods In a randomized …
treatment with benzodiazepines has not been thoroughly studied. Methods In a randomized …
Evidence-based guideline: treatment of convulsive status epilepticus in children and adults: report of the Guideline Committee of the American Epilepsy Society
T Glauser, S Shinnar, D Gloss, B Alldredge… - Epilepsy …, 2016 - journals.sagepub.com
CONTEXT: The optimal pharmacologic treatment for early convulsive status epilepticus is
unclear. OBJECTIVE: To analyze efficacy, tolerability and safety data for anticonvulsant …
unclear. OBJECTIVE: To analyze efficacy, tolerability and safety data for anticonvulsant …
THC and CBD: Similarities and differences between siblings
N Stella - Neuron, 2023 - cell.com
Summary Δ 9-tetrahydrocannabinol (THC) and its sibling, cannabidiol (CBD), are produced
by the same Cannabis plant and have similar chemical structures but differ dramatically in …
by the same Cannabis plant and have similar chemical structures but differ dramatically in …
A review of febrile seizures: recent advances in understanding of febrile seizure pathophysiology and commonly implicated viral triggers
Febrile seizures are one of the commonest presentations in young children, with a 2–5%
incidence in Western countries. Though they are generally benign, with rare long-term …
incidence in Western countries. Though they are generally benign, with rare long-term …
Levetiracetam versus phenytoin for second-line treatment of convulsive status epilepticus in children (ConSEPT): an open-label, multicentre, randomised controlled …
SR Dalziel, ML Borland, J Furyk, M Bonisch, J Neutze… - The Lancet, 2019 - thelancet.com
Background Phenytoin is the current standard of care for second-line treatment of paediatric
convulsive status epilepticus after failure of first-line benzodiazepines, but is only effective in …
convulsive status epilepticus after failure of first-line benzodiazepines, but is only effective in …
Why won't it stop? The dynamics of benzodiazepine resistance in status epilepticus
Status epilepticus is a life-threatening neurological emergency that affects both adults and
children. Approximately 36% of episodes of status epilepticus do not respond to the current …
children. Approximately 36% of episodes of status epilepticus do not respond to the current …
Pharmacotherapy for status epilepticus
Status epilepticus (SE) represents the most severe form of epilepsy. It is one of the most
common neurologic emergencies, with an incidence of up to 61 per 100,000 per year and …
common neurologic emergencies, with an incidence of up to 61 per 100,000 per year and …
Drug management for acute tonic‐clonic convulsions including convulsive status epilepticus in children
A McTague, T Martland… - Cochrane Database of …, 2018 - cochranelibrary.com
Background Tonic‐clonic convulsions and convulsive status epilepticus (currently defined
as a tonic‐clonic convulsion lasting at least 30 minutes) are medical emergencies and …
as a tonic‐clonic convulsion lasting at least 30 minutes) are medical emergencies and …