Neural stem cells exist not only in the developing mammalian nervous system but also in the
adult nervous system of all mammalian organisms, including humans. Neural stem cells can …

Oligodendrocytes, the myelin-forming cells of the central nervous system (CNS), and
astrocytes constitute macroglia. This review deals with the recent progress related to the …

Neurogenesis occurs in the dentate gyrus of the hippocampus throughout the life of a
rodent1–4, but the function of these new neurons and the mechanisms that regulate their …

The adult mammalian subventricular zone (SVZ) contains stem cells that give rise to
neurons and glia. In vivo, SVZ progeny migrate 3–8 mm to the olfactory bulb, where they …

Much excitement has been generated by the identification of adult brain regions harboring
neural stem cells and their continual generation of new neurons throughout life. This is an …

The adult brain is a plastic place. To ensure that the mature nervous system's control of
behaviour is flexible in the face of a varying environment, morphological and physiological …

Stem cells are a valuable resource for treating disease, but limited access to stem cells from
tissues such as brain restricts their utility. Here, we injected marrow stromal cells (MSCs) into …

The epidermal growth factor receptor (EGFR) is the prototypical member of a family of
membrane-associated intrinsic tyrosine kinase receptors, the ErbB family. EGFR is activated …

Malignant brain tumors strike deep into the psyche of those receiving and those delivering
the diagnosis. Malignant gliomas, the most common subtype of primary brain tumors, are …

Neurogenesis, which persists in the adult mammalian brain, may provide a basis for
neuronal replacement therapy in neurodegenerative diseases like Alzheimer's disease …