Glycocalyx and sepsis-induced alterations in vascular permeability

C Chelazzi, G Villa, P Mancinelli, AR De Gaudio… - Critical care, 2015 - Springer
Endothelial cells line the inner portion of the heart, blood vessels, and lymphatic vessels; a
basal membrane of extracellular matrix lines the extraluminal side of endothelial cells. The …

Randomized double-blind placebo-controlled trial of 40 mg/day of atorvastatin in reducing the severity of sepsis in ward patients (ASEPSIS Trial)

JM Patel, C Snaith, DR Thickett, L Linhartova, T Melody… - Critical care, 2012 - Springer
Introduction Several observational studies suggest that statins modulate the
pathophysiology of sepsis and may prevent its progression. The aim of this study was to …

Diabetic kidney disease: a systematic review on the role of epigenetics as diagnostic and prognostic marker

S Singh, SK Sonkar, GK Sonkar… - … Research and Reviews, 2019 - Wiley Online Library
Diabetic kidney disease is one of the most serious microvascular complications and among
the leading causes of end stage renal disease. Persistently increasing albuminuria has …

Acute reactive oxygen species (ROS)-dependent effects of IL-1β, TNF-α, and IL-6 on the glomerular filtration barrier (GFB) in vivo

K Sverrisson, J Axelsson, A Rippe… - American Journal …, 2015 - journals.physiology.org
This study was performed to investigate the immediate actions of the proinflammatory
cytokines IL-1β, TNF-α, and IL-6 on the permeability of the glomerular filtration barrier (GFB) …

Neutrophil gelatinase associated lipocalin as an indicator of acute kidney injury and inflammation in burned children

S Yavuz, A Anarat, S Acartürk, AC Dalay, E Kesiktaş… - Burns, 2014 - Elsevier
Introduction Neutrophil gelatinase associated lipocalin (NGAL) is a novel predictor of acute
kidney injury (AKI), which increases with inflammation. We aimed to assess whether serum …

Podocytes express IL-6 and lipocalin 2/neutrophil gelatinase-associated lipocalin in lipopolysaccharide-induced acute glomerular injury

SJ Lee, E Borsting, AE Declèves, P Singh… - Nephron Experimental …, 2012 - karger.com
Background/Aims: Acute kidney injury (AKI) contributes to significant morbidity and mortality
in the intensive care unit (ICU). Plasma levels of interleukin (IL)-6 predict the development of …

[PDF][PDF] Microalbuminuria can predict the development of acute kidney injury in critically ill septic patients

Z Zhang, B Lu, H Ni, X Sheng, N Jin - J Nephrol, 2013 - researchgate.net
Background: Microalbuminuria (MA) has long been as-sociated with development of chronic
kidney diseases in diabetic or hypertensive patients. However, its value in predicting acute …

Microalbuminuria: a biomarker of sepsis and efficacy of treatment in patients admitted to a medical intensive care unit of a tertiary referral center

RR Bhadade, R DeSouza, MJ Harde… - Journal of postgraduate …, 2014 - journals.lww.com
Background: The outcome of sepsis is significantly affected by early institution of goal-
directed therapies and hence, the search for an early marker of sepsis continues. Aims and …

Association of de novo dipstick albuminuria with severe acute kidney injury in critically ill septic patients

JA Neyra, J Manllo, X Li, G Jacobsen, J Yee… - Nephron Clinical …, 2015 - karger.com
Background: Acute kidney injury (AKI) occurs frequently in septic patients. Albuminuria may
play a role as an early marker of septic AKI. The potential association between de novo …

[HTML][HTML] Mortality prediction using acute physiology and chronic health evaluation II and acute physiology and chronic health evaluation IV scoring systems: Is there a …

R Venkataraman, V Gopichandran… - Indian Journal of …, 2018 - ncbi.nlm.nih.gov
Background: Mortality prediction in the Intensive Care Unit (ICU) setting is complex, and
there are several scoring systems utilized for this process. The Acute Physiology and …