After it was discovered approximately 40 years ago, carbohydrate antigen 125 (CA125)
became the most widely used and concerning biomarker in ovarian cancer screening …

Tumor-infiltrating lymphocytes (TILs), frontline soldiers of the adaptive immune system, are
recruited into the tumor site to fight against tumors. However, their small number and …

Increased levels of total tumor-infiltrating lymphocytes (TILs) are generally associated with
good prognosis in several breast cancer subtypes. Subtypes of TILs impact both tumor cells …

Cancer immunotherapy has evolved dramatically with improved understanding of immune
microenvironment and immunosurveillance. The immunogenicity of breast cancer is rather …

Background In this study, we investigated CD20+ TILs in triple-negative breast cancer
(TNBC) and their relationship with T lymphocyte subsets (CD4+, CD8+, CD25+, and …

Renal transplantation is currently the most effective treatment for end-stage renal disease.
However, chronic antibody-mediated rejection (cABMR) remains a serious obstacle for the …

As one of the most frequently diagnosed cancers, esophageal squamous cell carcinoma
(ESCC) remains the leading cause of malignancy‐related death worldwide. Many studies …

Regulatory B cells contribute to the regulation of immune responses in cancer, autoimmune
disorders, allergic conditions and inflammatory diseases. Although most studies focus on …

ABSTRACT B cells are emerging as key players of anti-tumor adaptive immune responses.
We investigated regulatory and pro-inflammatory cytokine-expressing B cells in patients with …

Pancreatic cancer is the most lethal tumor. CA125 (gene symbol MUC16) is an important
serum marker for pancreatic cancer diagnosis and treatment. High serum CA125 is related …