Cardiovascular disease (CVD) is the primary global cause of death, and inflammation is a
crucial factor in the development of CVDs. The acute phase inflammatory protein pentraxin 3 …

Severe infection can lead to sepsis. In sepsis, the host mounts an inappropriately large
inflammatory response in an attempt to clear the invading pathogen. This sustained high …

Background PTX3 is an important mediator of inflammation and innate immunity. We aimed
at assessing its prognostic value in a large cohort of patients hospitalized with COVID-19 …

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Thyroid is at the crossroads of immune dysregulation, tissue remodeling and oncogenesis.
Autoimmune disorders, nodular disease and cancer of the thyroid affect a large amount of …

Background The performance of host immune responses biomarkers and clinical scores
was compared to identify infection patient populations at risk of progression to sepsis, ICU …

Background: Preoperative diagnosis of periprosthetic joint infections (PJIs) poses an unmet
clinical challenge. The long pentraxin PTX3 is a component of the innate immune system …

The complement is a crucial immune defense system that triggers rapid immune responses
and offers efficient protection against foreign invaders and unwanted host elements, acting …

Background COVID-19 clinical course is highly variable and secondary infections contribute
to COVID-19 complexity. Early detection of secondary infections is clinically relevant for …

While the role of dysregulated polymorphonuclear leukocyte (PMN) transmigration in septic
mediated tissue damage is well documented, strategies to mitigate aberrant transmigration …