Bringing new life to damaged bone: the importance of angiogenesis in bone repair and regeneration

S Stegen, N Van Gastel, G Carmeliet - Bone, 2015 - Elsevier
Bone has the unique capacity to heal without the formation of a fibrous scar, likely because
several of the cellular and molecular processes governing bone healing recapitulate the …

[HTML][HTML] Role of the tumor microenvironment in tumor progression and the clinical applications

Y Yuan, YC Jiang, CK Sun… - Oncology reports, 2016 - spandidos-publications.com
Oncogene activation and tumor-suppressor gene inactivation are considered as the main
causes driving the transformation of normal somatic cells into malignant tumor cells. Cancer …

Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured …

A Desmoulière, A Geinoz, F Gabbiani… - The Journal of cell …, 1993 - rupress.org
Granulation tissue fibroblasts (myofibroblasts) develop several ultrastructural and
biochemical features of smooth muscle (SM) cells, including the presence of microfilament …

[HTML][HTML] Cancer associated fibroblasts (CAFs) in tumor microenvironment

F Xing, J Saidou, K Watabe - Frontiers in bioscience: a journal and …, 2010 - ncbi.nlm.nih.gov
Cancer associated fibroblasts (CAFs) is one of the most crucial components of the tumor
microenvironment which promotes the growth and invasion of cancer cells by various …

In search of the in vivo identity of mesenchymal stem cells

L da Silva Meirelles, AI Caplan, NB Nardi - Stem cells, 2008 - academic.oup.com
In spite of the advances in the knowledge of adult stem cells (ASCs) during the past few
years, their natural activities in vivo are still poorly understood. Mesenchymal stem cells …

Epithelial-mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy?

W Kriz, B Kaissling, M Le Hir - The Journal of clinical …, 2011 - Am Soc Clin Investig
Epithelial-mesenchymal transition (EMT) has become widely accepted as a mechanism by
which injured renal tubular cells transform into mesenchymal cells that contribute to the …

Solitary fibrous tumour and haemangiopericytoma: evolution of a concept

C Gengler, L Guillou - Histopathology, 2006 - Wiley Online Library
Haemangiopericytoma (HPC) was described in 1942 by Stout and Murray as a distinctive
soft tissue neoplasm, presumably of pericytic origin, exhibiting a characteristic well …

Heterogeneity of microvascular pericytes for smooth muscle type alpha-actin.

V Nehls, D Drenckhahn - The Journal of cell biology, 1991 - rupress.org
Microvascular pericytes are believed to be involved in various functions such as regulation
of capillary blood flow and endothelial proliferation. Since pericytes represent a …

Pericytes: cell biology and pathology

G Allt, JG Lawrenson - Cells tissues organs, 2001 - karger.com
Pericytes are perivascular cells with multifunctional activities which are now being
elucidated. The functional interaction of pericytes with endothelial cells (EC) is now being …

Capillary pericytes mediate coronary no-reflow after myocardial ischaemia

FM O'Farrell, S Mastitskaya, M Hammond-Haley… - elife, 2017 - elifesciences.org
After cardiac ischaemia, a prolonged decrease of coronary microvascular perfusion often
occurs even after flow is restored in an upstream artery. This' no-reflow'phenomenon …