Association between Impaired Ketogenesis and Metabolic-Associated Fatty Liver Disease

J Bae, BW Lee - Biomolecules, 2023 - mdpi.com
Metabolic (dysfunction) associated fatty liver disease (MAFLD) is generally developed with
excessive accumulation of lipids in the liver. Ketogenesis is an efficient pathway for the …

Fgr kinase is required for proinflammatory macrophage activation during diet-induced obesity

R Acín-Pérez, S Iborra, Y Martí-Mateos, ECL Cook… - Nature …, 2020 - nature.com
Proinflammatory macrophages are key in the development of obesity. In addition, reactive
oxygen species (ROS), which activate the Fgr tyrosine kinase, also contribute to obesity …

The efficacy of energy-restricted diets in achieving preoperative weight loss for bariatric patients: a systematic review

F Naseer, A Shabbir, B Livingstone, R Price, NL Syn… - Obesity surgery, 2018 - Springer
In bariatric practice, a preoperative weight loss of at least 5% is recommended. However, the
hypocaloric diets prescribed vary and no consensus exists. This study examined the efficacy …

Influence of a ketogenic diet, fish-oil, and calorie restriction on plasma metabolites and lipids in C57BL/6J mice

JJ Meidenbauer, N Ta, TN Seyfried - Nutrition & metabolism, 2014 - Springer
Background Diet therapies including calorie restriction, ketogenic diets, and fish-oil
supplementation have been used to improve health and to treat a variety of neurological and …

Kolaviron attenuates diclofenac-induced nephrotoxicity in male Wistar rats

QK Alabi, RO Akomolafe, MA Adefisayo… - Applied Physiology …, 2018 - cdnsciencepub.com
The beneficial effects of kolaviron, a natural biflavonoid from the seeds of Garcinia kola,
have been attributed to its antioxidant and anti-inflammatory activities. This study was …

Impaired ketogenesis is associated with metabolic-associated fatty liver disease in subjects with type 2 diabetes

S Lee, J Bae, DR Jo, M Lee, Y Lee, ES Kang… - Frontiers in …, 2023 - frontiersin.org
Aims The ketogenic pathway is an effective mechanism by which the liver disposes of fatty
acids (FAs) to the peripheral tissues. Impaired ketogenesis is presumed to be related to the …

Association between fasting ketonuria and advanced liver fibrosis in non-alcoholic fatty liver disease patients without prediabetes and diabetes mellitus

K Lim, M Kang, J Park - Nutrients, 2021 - mdpi.com
Ketone body production, an alternative fuel upon low glucose availability, reduces hepatic
fat accumulation. However, its clinical implications have not been established in patients …

Long-Term Fasting-Induced Ketosis in 1610 Subjects: Metabolic Regulation and Safety

F Grundler, R Mesnage, PMM Ruppert, D Kouretas… - Nutrients, 2024 - mdpi.com
Background: There is a growing consensus that fasting-induced ketosis has beneficial
effects on human physiology. Despite these compelling benefits, fasting-induced ketosis …

β-hydroxybutyrate as a biomarker of β-cell function in new-onset type 2 diabetes and its association with treatment response at 6 months

M Lee, Y Cho, Y Lee, ES Kang, B Cha, BW Lee - Diabetes & Metabolism, 2023 - Elsevier
Aims Increasing attention has been paid to the potential metabolic benefits of ketone bodies,
but the clinical relevance of ketone bodies in newly diagnosed type 2 diabetes mellitus …

Prevalence of ketosis, ketonuria, and ketoacidosis during liberal glycemic control in critically ill patients with diabetes: an observational study

N Luethi, L Cioccari, M Crisman, R Bellomo… - Critical Care, 2016 - Springer
Background It is uncertain whether liberal glucose control in critically ill diabetic patients
leads to increased ketone production and ketoacidosis. Therefore, we aimed to assess the …