Cancer vaccine therapeutics: limitations and effectiveness—A literature review

M Kaczmarek, J Poznańska, F Fechner, N Michalska… - Cells, 2023 - mdpi.com
In recent years, there has been a surge of interest in tumor microenvironment-associated
cancer vaccine therapies. These innovative treatments aim to activate and enhance the …

Nanomedicine embraces cancer radio-immunotherapy: mechanism, design, recent advances, and clinical translation

H Li, Q Luo, H Zhang, X Ma, Z Gu, Q Gong… - Chemical Society …, 2023 - pubs.rsc.org
Cancer radio-immunotherapy, integrating external/internal radiation therapy with immuno-
oncology treatments, emerges in the current management of cancer. A growing number of …

Reigniting hope in cancer treatment: the promise and pitfalls of IL-2 and IL-2R targeting strategies

S Muhammad, T Fan, Y Hai, Y Gao, J He - Molecular Cancer, 2023 - Springer
Abstract Interleukin-2 (IL-2) and its receptor (IL-2R) are essential in orchestrating immune
responses. Their function and expression in the tumor microenvironment make them …

Peptide-based vaccine for cancer therapies

L Buonaguro, M Tagliamonte - Frontiers in Immunology, 2023 - frontiersin.org
Different strategies based on peptides are available for cancer treatment, in particular to
counter-act the progression of tumor growth and disease relapse. In the last decade, in the …

Responsive multivesicular polymeric nanovaccines that codeliver STING agonists and neoantigens for combination tumor immunotherapy

T Su, F Cheng, J Qi, Y Zhang, S Zhou, L Mei… - Advanced …, 2022 - Wiley Online Library
Immune checkpoint blockade (ICB) has significantly advanced cancer immunotherapy, yet
its patient response rates are generally low. Vaccines, including immunostimulant …

Black phosphorus, an emerging versatile nanoplatform for cancer immunotherapy

H Liu, Y Mei, Q Zhao, A Zhang, L Tang, H Gao… - Pharmaceutics, 2021 - mdpi.com
Black phosphorus (BP) is one of the emerging versatile nanomaterials with outstanding
biocompatibility and biodegradability, exhibiting great potential as a promising inorganic …

Modulation of the tumor microenvironment (TME) by melatonin

Q Mu, M Najafi - European journal of pharmacology, 2021 - Elsevier
The tumor microenvironment (TME) includes a number of non-cancerous cells that affect
cancer cell survival. Although CD8+ T lymphocytes and natural killer (NK) cells suppress …

Cancer vaccines: Promising therapeutics or an unattainable dream

H Donninger, C Li, JW Eaton, K Yaddanapudi - Vaccines, 2021 - mdpi.com
The advent of cancer immunotherapy has revolutionized the field of cancer treatment and
offers cancer patients new hope. Although this therapy has proved highly successful for …

Combining cancer vaccines with immunotherapy: establishing a new immunological approach

CG Kim, YB Sang, JH Lee, HJ Chon - International Journal of Molecular …, 2021 - mdpi.com
Therapeutic cancer vaccines have become increasingly qualified for use in personalized
cancer immunotherapy. A deeper understanding of tumor immunology and novel antigen …

Current status of nano‐vaccinology in veterinary medicine science

S Sadr, P Poorjafari Jafroodi… - Veterinary Medicine …, 2023 - Wiley Online Library
Vaccination programmes provide a safe, effective and cost‐efficient strategy for maintaining
population health. In veterinary medicine, vaccination not only reduces disease within …