Treatment of late sequelae after radiotherapy for head and neck cancer

P Strojan, KA Hutcheson, A Eisbruch, JJ Beitler… - Cancer treatment …, 2017 - Elsevier
Radiotherapy (RT) is used to treat approximately 80% of patients with cancer of the head
and neck. Despite enormous advances in RT planning and delivery, a significant number of …

Radiation-induced salivary gland dysfunction: mechanisms, therapeutics and future directions

KJ Jasmer, KE Gilman, K Muñoz Forti… - Journal of clinical …, 2020 - mdpi.com
Salivary glands sustain collateral damage following radiotherapy (RT) to treat cancers of the
head and neck, leading to complications, including mucositis, xerostomia and …

Pathophysiology of radiation-induced dysphagia in head and neck cancer

SN King, NE Dunlap, PA Tennant, T Pitts - Dysphagia, 2016 - Springer
Oncologic treatments, such as curative radiotherapy and chemoradiation, for head and neck
cancer can cause long-term swallowing impairments (dysphagia) that negatively impact …

The prevalence of patient-reported dysphagia and oral complications in cancer patients

J Frowen, R Hughes, J Skeat - Supportive Care in Cancer, 2020 - Springer
Purpose Research investigating swallowing problems (dysphagia) and complications within
the oral cavity in non-head and neck cancer patients is limited. The purpose of this study …

Changes in nutrition impact symptoms, nutritional and functional status during head and neck cancer treatment

MK Neoh, Z Abu Zaid, ZA Mat Daud, NB Md. Yusop… - Nutrients, 2020 - mdpi.com
Background: The purpose of this study is to evaluate changes in nutrition impact symptoms
(NIS) and nutritional and functional status that occur throughout radiotherapy in head and …

Predictive factors for chemoradiation-induced oral mucositis and dysphagia in head and neck cancer: a scoping review

AJ Nicol, JCF Ching, VCW Tam, KCK Liu, VWS Leung… - Cancers, 2023 - mdpi.com
Simple Summary Head and neck cancer is the seventh-most prevalent cancer worldwide.
Despite advances in treatment, many patients suffer from chemoradiation-induced oral …

Beyond mean pharyngeal constrictor dose for beam path toxicity in non-target swallowing muscles: dose–volume correlates of chronic radiation-associated dysphagia …

T Dale, K Hutcheson, ASR Mohamed, JS Lewin… - Radiotherapy and …, 2016 - Elsevier
Purpose/objective (s) We sought to identify swallowing muscle dose–response thresholds
associated with chronic radiation-associated dysphagia (RAD) after IMRT for oropharyngeal …

Nutritional experiences in head and neck cancer patients

JA Sandmæl, K Sand, A Bye… - European journal of …, 2019 - Wiley Online Library
Objective Extensive research has documented the negative nutritional impact of head neck
cancer (HNC) treatment, but few studies have addressed the patients' experiences. The …

Metabolomics analysis of pathways underlying radiation-induced salivary gland dysfunction stages

LG Buss, D De Oliveira Pessoa, JM Snider, M Padi… - PLoS …, 2023 - journals.plos.org
Salivary gland hypofunction is an adverse side effect associated with radiotherapy for head
and neck cancer patients. This study delineated metabolic changes at acute, intermediate …

Voxel-based analysis unveils regional dose differences associated with radiation-induced morbidity in head and neck cancer patients

S Monti, G Palma, V D'Avino, M Gerardi, G Marvaso… - Scientific reports, 2017 - nature.com
The risk of radiation-induced toxicity in patients treated for head and neck (HN) cancer with
radiation therapy (RT) is traditionally estimated by condensing the 3D dose distribution into …