Several studies have shown that epitope vaccines exhibit substantial advantages over
conventional vaccines. However, epitope vaccines are associated with limited immunity …

Tuberculosis (TB), a life threatening communicable disease, is mainly caused by the
bacterium named Mycobacterium tuberculosis (MTB). This high burden infectious threat is …

Group A streptococcal infections are a significant cause of global morbidity and mortality. A
leading vaccine candidate is the surface M protein, a major virulence determinant and …

Background: To combat the tuberculosis (TB) epidemic, the development of a better and
faster diagnosis or more effective vaccine is essential. Pulmonary TB (PTB) is one of the …

Mycobacterium tuberculosis (MTB) causes one of the ancient diseases, Tuberculosis, affects
people around the globe and its severity can be understood by its classification as a second …

Tuberculosis, caused by Mycobacterium tuberculosis bacillus, is one of the most prevalent,
widespread, infectious, and deadliest diseases in the world. In this work, a compact and …

Background Resistance to anti-tuberculosis (TB) drugs is a major issue in TB control, and
demands the discovery of new drugs targeting the virulence factor ESX-1. Methods We first …

Tuberculosis (TB) is a highly infectious disease and its early and precise diagnosis is
essential to reduce morbidity and mortality of patients. Since the routine diagnostic tests (like …

Tuberculosis remains a serious global health problem. BCG is the only prophylactic TB
vaccine and it shows variable protective efficacy. Chimeric protein subunit vaccines hold …

Mycobacterium tuberculosis causes Tuberculosis (TB), the leading cause of death globally
from a single infectious disease. TB eradication will require improved control strategies …