Understanding the thermodynamics of drug binding to DNA is of both practical and
fundamental interest. The practical interest lies in the contribution that thermodynamics can …

Several aspects of the intercalation of organic dyes into DNA are presented. After a
description of general features of intercalation and the analytical evaluation of this binding …

MATERIALS AND METHODS Ruthenium Compounds. The synthesis and resolution of the
ruthenium compounds were as earlier described (Dwyer & Gyarfas, 1949; Dwyer et al …

The structure, function and reactions of nucleic acids are central to molecular biology and
are crucial for the understanding of complex biological processes involved. Revised and …

Fluorescence and absorption spectroscopy, isothermal titration calorimetry, and viscosity
measurements have been used to characterize the interaction of and A [Ru (phen) 2DPPZ] …

The interactions of small molecules with nucleic acids have provoked considerable interest
in the field of anticancer drug design over the past three decades; however, critical …

The intercalation process of binding doxorubicin (DOX) in DNA is studied by extensive MD
simulations. Many molecular factors that control the binding affinity of DOX to DNA to form a …

Die Entwicklung von Molekülen, die selektiv an Nucleinsäuren binden können, hat eine
ganze Reihe von Details über DNA-und RNA-Erkennungsprozesse geliefert. Die Palette an …

A major contribution to the binding free energy associated with most protein-nucleic acid
complexes is the increase in entropy due to counterion release from the nucleic acid that …

We review some of the characteristic properties of the structure of polyelectrolyte solutions:
the condensed layer of counterions that forms abruptly at a critical threshold charge density …