Fifty years of the schistosome tegument: discoveries, controversies, and outstanding questions

RA Wilson, MK Jones - International Journal for Parasitology, 2021 - Elsevier
The unique multilaminate appearance of the tegument surface of schistosomes was first
described in 1973, in one of the earliest volumes of the International Journal for …

Diagnostic performances of Schistosoma haematobium and Schistosoma mansoni recombinant proteins, peptides and chimeric proteins antibody based tests …

A Vengesai, V Muleya, H Midzi, TV Tinago, I Chipako… - Plos one, 2023 - journals.plos.org
Background Traditional diagnostic tests for schistosome infections are suboptimal,
particularly when the parasite burden is low. In the present review we sought to identify …

Fasciola hepatica Extracellular Vesicles isolated from excretory-secretory products using a gravity flow method modulate dendritic cell phenotype and activity

A Murphy, K Cwiklinski, R Lalor… - PLoS neglected …, 2020 - journals.plos.org
Parasite-released extracellular vesicles (EVs) deliver signals to the host immune system that
are critical to maintaining the long-term relationship between parasite and host. In the …

[HTML][HTML] The most prominent modulated annexins during parasitic infections

S Rashidi, R Mansouri, M Ali-Hassanzadeh, A Muro… - Acta Tropica, 2023 - Elsevier
Annexins (ANXs) exert different functions in cell biological and pathological processes and
are thus known as double or multi-faceted proteins. These sophisticated proteins might …

Design of Broadly Cross-Reactive M Protein–Based Group A Streptococcal Vaccines

MP Aranha, TA Penfound, S Salehi… - The Journal of …, 2021 - journals.aai.org
Group A streptococcal infections are a significant cause of global morbidity and mortality. A
leading vaccine candidate is the surface M protein, a major virulence determinant and …

Molecular and functional characterization of Schistosoma japonicum annexin A13

H Zhong, L Hou, F Qin, Y Ren, B Dong, D Zhu, H Li… - Veterinary …, 2023 - Springer
Schistosomiasis is a neglected tropical disease that affects humans and animals in tropical
and subtropical regions worldwide. Schistosome eggs are responsible for the pathogenesis …

Synergistic effect of combination chemotherapy with praziquantel and DW-3-15 for Schistosoma japonicum in vitro and in vivo

ZY Yang, ZH Liu, YN Zhang, C Li, L Liu, WJ Pu… - Parasites & vectors, 2021 - Springer
Background Schistosomiasis is a debilitating and neglected tropical disease for which
praziquantel (PZQ) remains the first-choice drug for treatment and control of the disease. In …

Identification and Immunological Characterization of Annexin B8 and Annexin E1 from Spirometra Erinaceieuropaei Spargana

R Fu, Y Xu, G Lu, F Zhang, P Liang, D Wang - Parasitology Research, 2024 - Springer
Sparganosis is a parasitic zoonotic disease that poses a serious threat to public hygiene
and human health. Annexin is a phospholipid-binding protein with calcium ion binding …

Annexin gene family in Spirometra mansoni (Cestoda: Diphyllobothriidae) and its phylogenetic pattern among Platyhelminthes of medical interest

XY Su, F Gao, SY Wang, J Li, ZQ Wang, X Zhang - Parasite, 2024 - pmc.ncbi.nlm.nih.gov
The plerocercoid larvae of Spirometra mansoni are etiological agents of human and animal
sparganosis. Annexins are proteins with important roles in parasites. However, our …

Annexin in Taenia crassiceps ORF Strain is Localized in the Osmoregulatory System

DG Rios-Valencia, Y Mompala-García… - Acta Parasitologica, 2022 - Springer
Purpose Annexins are proteins with important roles in parasites, some of which are related
to excretion–secretion processes, protein traffic, and microvesicle functionality. The …