Clinical end points in coronary stent trials: a case for standardized definitions

DE Cutlip, S Windecker, R Mehran, A Boam… - Circulation, 2007 - Am Heart Assoc
Background—Although most clinical trials of coronary stents have measured nominally
identical safety and effectiveness end points, differences in definitions and timing of …

Prevention of premature discontinuation of dual antiplatelet therapy in patients with coronary artery stents: a science advisory from the American Heart Association …

CL Grines, RO Bonow, DE Casey Jr, TJ Gardner… - Circulation, 2007 - Am Heart Assoc
Dual antiplatelet therapy with aspirin and a thienopyridine has been shown to reduce
cardiac events after coronary stenting. However, many patients and healthcare providers …

Stent thrombogenicity early in high-risk interventional settings is driven by stent design and deployment and protected by polymer-drug coatings

K Kolandaivelu, R Swaminathan, WJ Gibson… - Circulation, 2011 - Am Heart Assoc
Background—Stent thrombosis is a lethal complication of endovascular intervention.
Concern has been raised about the inherent risk associated with specific stent designs and …

Pathology of drug-eluting stents in humans: delayed healing and late thrombotic risk

M Joner, AV Finn, A Farb, EK Mont, FD Kolodgie… - Journal of the American …, 2006 - jacc.org
Objectives: This study examined human drug-eluting stents (DES) to determine the long-
term effects of these stents on coronary arterial healing and identified mechanisms …

Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents

I Iakovou, T Schmidt, E Bonizzoni, L Ge, GM Sangiorgi… - Jama, 2005 - jamanetwork.com
ContextTraditionally, stent thrombosis has been regarded as a complication of percutaneous
coronary interventions during the first 30 postprocedural days. However, delayed …

Predictors of coronary stent thrombosis: the Dutch Stent Thrombosis Registry

JW Van Werkum, AA Heestermans, AC Zomer… - Journal of the American …, 2009 - jacc.org
Objectives: This study sought to comprehensively identify predictors of stent thrombosis (ST).
Background: Given the devastating consequences of ST, efforts should be directed toward …

Drug-eluting stent and coronary thrombosis: biological mechanisms and clinical implications

TF Lüscher, J Steffel, FR Eberli, M Joner… - Circulation, 2007 - Am Heart Assoc
Although rare, stent thrombosis remains a severe complication after stent implantation owing
to its high morbidity and mortality. Since the introduction of drug-eluting stents (DES), most …

A cause for concern

E Camenzind, PG Steg, W Wijns - Circulation, 2007 - Am Heart Assoc
1440 and clinical studies, we propose that the pathophysiological mechanisms known as
Virchow's triad may be responsible for LST with gen1-DES. 53 Furthermore, we comment on …

Recent advances and directions in the development of bioresorbable metallic cardiovascular stents: insights from recent human and in vivo studies

AA Oliver, M Sikora-Jasinska, AG Demir, RJ Guillory II - Acta Biomaterialia, 2021 - Elsevier
Over the past two decades, significant advancements have been made regarding the
material formulation, iterative design, and clinical translation of metallic bioresorbable stents …

Stent thrombosis in the modern era: a pooled analysis of multicenter coronary stent clinical trials

DE Cutlip, DS Baim, KKL Ho, JJ Popma, AJ Lansky… - Circulation, 2001 - Am Heart Assoc
Background—There are limited studies of stent thrombosis in the modern era of second-
generation stents, high-pressure deployment, and current antithrombotic regimens. Methods …