With disease-modifying drugs on the horizon for degenerative ataxias, ecologically valid,
finely granulated, digital health measures are highly warranted to augment clinical and …

Friedreich ataxia (FRDA) is an autosomal-recessive disorder characterized by progressive
neurological and cardiac abnormalities. It predominantly affects individuals of European and …

Background and Objectives The understanding of the natural history of Friedreich ataxia
(FRDA) has improved considerably recently, but patterns of neurologic deterioration are not …

Background We assessed the clinimetric properties of ataxia rating scales and functional
tests, and made recommendations regarding their use. Methods A systematic literature …

Cerebellar and afferent ataxias present with a characteristic gait disorder that reflects
cerebellar motor dysfunction and sensory loss. These disorders are a diagnostic challenge …

Objective The natural history of Friedreich ataxia is being investigated in a multi‐center
longitudinal study designated the Friedreich ataxia Clinical Outcome Measures Study …

Objective Friedreich ataxia (FRDA) is an inherited neurological disease defined by
progressive movement incoordination. We undertook a comprehensive characterization of …

Background Friedreich's ataxia (FRDA) is a characterized by progressive loss of
coordination and balance leading to loss of ambulation (LoA) in nearly all affected …

Summary Background The European Friedreich's Ataxia Consortium for Translational
Studies (EFACTS) investigates the natural history of Friedreich's ataxia. We aimed to assess …

The life shortening nature of Friedreich Ataxia (FRDA) demands the search for therapies that
can delay, stop or reverse its relentless trajectory. This review provides a contemporary …