Programmed cell death (PCD) or apoptosis is a mechanism which is crucial for all
multicellular organisms to control cell proliferation and maintain tissue homeostasis as well …

Survivin is one of the most cancer-specific proteins identified to date, being upregulated in
almost all human tumors. Biologically, survivin has been shown to inhibit apoptosis …

Since the discovery of survivin (BIRC5) as a cancer-related molecule by Grazia Ambrosini
and Dario C. Altieri at 1997, our knowledge related to the function of this molecule has been …

Background Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease with a poor
prognosis. Pirfenidone is the first antifibrotic agent to be approved for IPF-treatment as it is …

Abstract Ganoderma atrum polysaccharide (PSG‐1), the major active ingredient isolated
from Ganoderma atrum, has been suggested as a candidate for cancer therapy. The aim of …

Malignant glioma represents the most common primary adult brain tumor in Western
industrialized countries. Despite aggressive treatment modalities, the median survival …

Accumulating evidence indicates that microbial communities in the human body crucially
affect health through the production of chemical messengers. However, the relationship …

Recently, survivin has been attracting great attention because it plays an important role in
inhibiting the apoptosis process of tumor cells. Down-regulating the expression of survivin …

Head and neck squamous cell carcinoma (HNSCC) is the sixth most commonly diagnosed
cancer worldwide. It has poor clinical outcome due to intrinsic or acquired drug resistance …

In recent years, cyclic peptides have attracted much attention due to their chemical and
enzymatic stability, low toxicity, and easy modification. In general, the self-assembled …