Vitamin D in neurological diseases

D Plantone, G Primiano, C Manco, S Locci… - International journal of …, 2022 - mdpi.com
Vitamin D may have multiple effects on the nervous system and its deficiency can represent
a possible risk factor for the development of many neurological diseases. Recent studies are …

Vitamin D supplementation in multiple sclerosis: a critical analysis of potentials and threats

J Feige, T Moser, L Bieler, K Schwenker, L Hauer… - Nutrients, 2020 - mdpi.com
Multiple sclerosis (MS) is a chronic inflammatory demyelinating and neurodegenerative
disease of the central nervous system (CNS). In recent years, vitamin D has gained …

Full spectrum of vitamin D immunomodulation in multiple sclerosis: Mechanisms and therapeutic implications

M Galoppin, S Kari, S Soldati, A Pal… - Brain …, 2022 - academic.oup.com
Vitamin D deficiency has been associated with the risk of multiple sclerosis, disease activity
and progression. Results from in vitro experiments, animal models and analysis of human …

An update on vitamin D and disease activity in multiple sclerosis

J Smolders, Ø Torkildsen, W Camu, T Holmøy - CNS drugs, 2019 - Springer
Vitamin D and its main active metabolite 1, 25-dihydroxyvitamin D serve a crucial role in
maintenance of a healthy calcium metabolism, yet have additional roles in immune and …

[HTML][HTML] Molecular insights into the pathogenic impact of vitamin D deficiency in neurological disorders

MJ Anwar, SK Alenezi, AH Alhowail - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Neurological disorders are the major cause of disability, leading to a decrease in quality of
life by impairing cognitive, sensorimotor, and motor functioning. Several factors have been …

Vitamin D for the treatment of multiple sclerosis: a meta-analysis

L McLaughlin, L Clarke, E Khalilidehkordi… - Journal of …, 2018 - Springer
Objective There is an association between latitude, relative vitamin D deficiency and risk of
multiple sclerosis (MS), and an association between vitamin D and disease progression. We …

Vitamin D: immune function, inflammation, infections and auto-immunity

CR Johnson, TD Thacher - Paediatrics and International Child …, 2023 - Taylor & Francis
Vitamin D plays an active role beyond mineral metabolism and skeletal health, including
regulation of the immune system. Vitamin D deficiency is widely prevalent, and …

Genomic effects of the vitamin D receptor: potentially the link between vitamin D, immune cells, and multiple sclerosis

M Lu, BV Taylor, H Körner - Frontiers in immunology, 2018 - frontiersin.org
Vitamin D has a plethora of functions that are important for the maintenance of general
health and in particular, the functional integrity of the immune system, such as promoting an …

Vitamin D supplementation in multiple sclerosis: An expert opinion based on the review of current evidence

R Boltjes, S Knippenberg, O Gerlach… - Expert Review of …, 2021 - Taylor & Francis
Introduction Vitamin D has long been known for its immune-modulating effects, next to its
function in calcium metabolism. As a consequence, poor vitamin D status has been …

Clinical and imaging outcomes after vitamin D supplementation in patients with Multiple Sclerosis: A systematic review

J Langlois, D Denimal - Nutrients, 2023 - mdpi.com
The link between vitamin D and multiple sclerosis (MS) has been suggested in
epidemiological, genetic, immunological, and clinical studies. The aim of the present …