The oral microbiome can play a role in the instigation and progression of oral diseases that
can manifest into other systemic conditions. These associations encourage the exploration …

Abstract Purpose Circulating tumour cells (CTCs) are a rare cell subpopulation regulated by
the tumour microenvironment. In hypoxic conditions, CTCs are able to invade the lymphatic …

Background Patients with oral cavity cancer (OCC) and oropharyngeal cancer (OPC) are
often seen with locoregionally advanced disease requiring complex multimodality …

Immune checkpoint inhibitors have gained traction over the last few years in the treatment of
metastatic/recurrent head and neck squamous cell carcinoma (HNSCC) patients …

Objectives: Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous tumour
type which necessitates multiple invitro models to attain an appreciation of its multiple …

Circulating tumour cells (CTCs) have the potential to transform the management of patients
with non-small cell lung cancer (NSCLC). The applications of CTCs can identify clinically …

The management of head and neck cancer (HNC) using radiotherapy+/-chemotherapy (C)
RT is associated with significant morbidity, due to key structures required for speech …

This project is a pilot proof of concept aimed at investigating the human oral microbiome
profile changes in healthy individual and cancer patient using saliva samples. The …