Reactions, which permit the selective deprotection of one silyl-protected alcohol in the
presence of another are reviewed. This review covers examples reported in the literature …

We present the first examples of tethered olefin functionalization reactions using a silanol
auxiliary. A range of allylic alcohols are readily condensed with di-tert-butylsilyl bis …

This is a review of papers published in the year 2009 that focus on the synthesis, reactivity,
or properties of compounds containing a carbon-transition metal double or triple bond.

The impressive biological profile of secondary metabolites isolated from strains of
Sorangium cellulosum prompted us to initiate synthetic studies on kulkenon, also isolated …

In this communication, we report that substrate-controlled 1, 5-syn and-anti stereoinduction
in the aldol reaction of β-tris (trialkylsilyl) siloxy methyl ketones can be achieved with high …

The total syntheses of amphidinolide B1 and the proposed structure of amphidinolide B2
have been accomplished. Key aspects of this work include the development of a practical …

The brasilinolides are an architecturally complex family of 32-membered macrolides,
characterised by potent immunosuppressant and antifungal properties, which represent …

Synthetic studies toward the spiroketal core of spirangien A are described. Two synthetic
approaches were developed. Both of them use a diastereoselective aldol addition of a …

A growing number of complex polyketides, isolated from a variety of marine and terrestrial
sources, present novel scaffolds for the development of cancer therapeutic agents. However …

An efficient, convergent synthesis of a differentially protected C20− C38 segment of the
brasilinolides is described. Iterative 1, 4-syn aldol additions and ketone reductions were …