Offspring physiology following the use of IVM, IVF and ICSI: a systematic review and meta-analysis of animal studies

KH Beilby, E Kneebone, TJ Roseboom… - Human reproduction …, 2023 - academic.oup.com
BACKGROUND Since the birth of the first baby using IVF technology in 1978, over 10 million
children have been conceived via ART. Although most aspects of ARTs were developed in …

Cryopreservation of gametes and embryos and their molecular changes

E Estudillo, A Jiménez, PE Bustamante-Nieves… - International Journal of …, 2021 - mdpi.com
The process of freezing cells or tissues and depositing them in liquid nitrogen at–196° C is
called cryopreservation. Sub-zero temperature is not a physiological condition for cells and …

Discovery of the major 15–30 nt mammalian small RNAs, their biogenesis and function

H Lai, N Feng, Q Zhai - Nature Communications, 2023 - nature.com
Abstract Small RNAs (sRNAs) within 15-30 nt such as miRNA, tsRNA, srRNA with 3'-OH
have been identified. However, whether these sRNAs are the major 15-30 nt sRNAs is still …

The mammalian preimplantation embryo: its role in the environmental programming of postnatal health and performance

MA Velazquez, A Idriss, P Chavatte-Palmer… - Animal Reproduction …, 2023 - Elsevier
During formation of the preimplantation embryo several cellular and molecular milestones
take place, making the few cells forming the early embryo vulnerable to environmental …

Developmental origins of diabetes mellitus: Environmental epigenomics and emerging patterns

H Zhu, G Ding, X Liu, H Huang - Journal of diabetes, 2023 - Wiley Online Library
Mounting epidemiological evidence indicates that environmental exposures in early life
have roles in diabetes susceptibility in later life. Additionally, environmentally induced …

Altered local RAS in the liver increased the risk of NAFLD in male mouse offspring produced by in vitro fertilization

L Bo, L Wei, L Shi, C Luo, S Gao, A Zhou… - BMC Pregnancy and …, 2023 - Springer
Background Assisted reproductive technology (ART) is associated with an increased risk of
adverse metabolic health in offspring, and these findings have been demonstrated in animal …

Metabolic profiles of children aged 2–5 years born after frozen and fresh embryo transfer: A Chinese cohort study

W Zhou, W Feng, J Chang, J Hu, F Li, K Hu, J Jiao… - PLoS …, 2024 - journals.plos.org
Background Frozen embryo transfer (FET) has become a widely employed assisted
reproductive technology technique. There have historically been concerns regarding the …

Long-term health risk of offspring born from assisted reproductive Technologies

S Zhang, Q Luo, R Meng, J Yan, Y Wu… - Journal of Assisted …, 2024 - Springer
Since the world's first in vitro fertilization baby was born in 1978, there have been more than
8 million children conceived through assisted reproductive technologies (ART) worldwide …

Assisted reproductive technology and imprinting errors: analyzing underlying mechanisms from epigenetic regulation

G Zhang, Y Mao, Y Zhang, H Huang, J Pan - Human Fertility, 2023 - Taylor & Francis
With the increasing maturity and widespread application of assisted reproductive technology
(ART), more attention has been paid to the health outcomes of offspring following ART. It is …

Laccaic acid restores epigenetic alterations responsible for high fat diet induced insulin resistance in C57BL/6J mice

SW Kabeer, R Pant, S Sharma, K Tikoo - Chemico-Biological Interactions, 2023 - Elsevier
Laccaic acid, the major constituent of the food colouring agent-lac dye, possesses
antioxidant and anti-inflammatory properties. Here we have evaluated the effects of laccaic …