Gastroesophageal reflux disease (GERD) is a disorder due to the retrograde flow of
refluxate into the esophagus. Although GERD is a common clinical diagnosis, its …

The community prevalence of dyspepsia ranges from 20% to 40%, and dyspepsia accounts
for 3% to 5% of primary care visits. Dyspepsia symptoms include epigastric pain, epigastric …

Background: Non‐ulcer dyspepsia is predominantly a self‐managed condition, although it
accounts for a significant number of general practitioner consultations and hospital referrals …

Background To seek a promising therapeutic regimen for proton pump inhibitor (PPI)-
refractory patients with gastroesophageal reflux disease (GERD) after the standard PPI …

Background Rikkunshito, a traditional Japanese (Kampo) medicine, is widely prescribed as
an oral preparation for the treatment of functional dyspepsia (FD). In our previous study, we …

The pathophysiology of functional gastrointestinal disorders (FGIDs) is still unclear and
various complex mechanisms have been suggested to be involved. In many cases …

We evaluated the effects of Rikkunshi-to and several of its ingredients on the delay of gastric
emptying induced by a nitric oxide (NO) synthase inhibitor, Ng-nitro-L-arginine (L-NNA) …

The effect of rhizomes of Atractylodes lancea on gastric disorders, in particular, the delay in
gastric emptying induced by NG-nitro-l-arginine in rats, was investigated. Intragastric …

Management of functional gastrointestinal disorders is hindered by both poor efficacy and
adverse effects of traditional pharmacological therapy. Herbal medicine may be an attractive …

The traditional Japanese medicine rikkunshito ameliorates the nitric oxide‐associated delay
in gastric emptying. Whether rikkunshito affects gastric motility associated with 5 …