[HTML][HTML] The inner blood-retinal barrier: Cellular basis and development

M Díaz-Coránguez, C Ramos, DA Antonetti - Vision research, 2017 - Elsevier
The blood-retinal barrier (BRB) regulates transport across retinal capillaries maintaining
proper neural homeostasis and protecting the neural tissue from potential blood borne …

Lipolysis and lipid mobilization in human adipose tissue

M Lafontan, D Langin - Progress in lipid research, 2009 - Elsevier
Triacylglycerol (TAG) stored in adipose tissue (AT) can be rapidly mobilized by the hydrolytic
action of the three main lipases of the adipocyte. The non-esterified fatty acids (NEFA) …

Structure, function and pathophysiology of protease activated receptors

MN Adams, R Ramachandran, MK Yau, JY Suen… - Pharmacology & …, 2011 - Elsevier
Discovered in the 1990s, protease activated receptors 1 (PARs) are membrane-spanning
cell surface proteins that belong to the G protein coupled receptor (GPCR) family. A defining …

Endothelial glycocalyx as a shield against diabetic vascular complications: involvement of hyaluronan and hyaluronidases

S Dogné, B Flamion, N Caron - Arteriosclerosis, thrombosis, and …, 2018 - Am Heart Assoc
The endothelial glycocalyx (EG), which covers the apical surface of the endothelial cells and
floats into the lumen of the vessels, is a key player in vascular integrity and cardiovascular …

A narrative role of vitamin D and its receptor: with current evidence on the gastric tissues

S Sirajudeen, I Shah, A Al Menhali - International journal of molecular …, 2019 - mdpi.com
Vitamin D is a major steroid hormone that is gaining attention as a therapeutic molecule.
Due to the general awareness of its importance for the overall well-being, vitamin D …

Exchange protein directly activated by cAMP (epac): a multidomain cAMP mediator in the regulation of diverse biological functions

M Schmidt, FJ Dekker, H Maarsingh, MC Michel - Pharmacological reviews, 2013 - Elsevier
Since the discovery nearly 60 years ago, cAMP is envisioned as one of the most universal
and versatile second messengers. The tremendous feature of cAMP to tightly control highly …

Endocytosis and signaling: cell logistics shape the eukaryotic cell plan

S Sigismund, S Confalonieri, A Ciliberto… - Physiological …, 2012 - journals.physiology.org
Our understanding of endocytosis has evolved remarkably in little more than a decade. This
is the result not only of advances in our knowledge of its molecular and biological workings …

Sphingosine 1-phosphate receptor signaling

H Rosen, PJ Gonzalez-Cabrera… - Annual review of …, 2009 - annualreviews.org
The sphingosine 1-phosphate (S1P) receptor signaling system is a productive model
system. A hydrophobic zwitterionic lysophospholipid ligand with difficult physical properties …

The vital role for nitric oxide in intraocular pressure homeostasis

E Reina-Torres, ML De Ieso, LR Pasquale… - Progress in retinal and …, 2021 - Elsevier
Catalyzed by endothelial nitric oxide (NO) synthase (eNOS) activity, NO is a gaseous
signaling molecule maintaining endothelial and cardiovascular homeostasis. Principally, NO …

Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma

G Thorleifsson, GB Walters, AW Hewitt, G Masson… - Nature …, 2010 - nature.com
We conducted a genome-wide association study for primary open-angle glaucoma (POAG)
in 1,263 affected individuals (cases) and 34,877 controls from Iceland. We identified a …