Pemphigus: current and future therapeutic strategies

D Didona, R Maglie, R Eming, M Hertl - Frontiers in immunology, 2019 - frontiersin.org
Pemphigus encompasses a heterogeneous group of autoimmune blistering diseases, which
affect both mucous membranes and the skin. The disease usually runs a chronic-relapsing …

Autoimmune subepidermal bullous diseases of the skin and mucosae: clinical features, diagnosis, and management

KT Amber, DF Murrell, E Schmidt, P Joly… - Clinical reviews in allergy …, 2018 - Springer
Autoimmune subepidermal blistering diseases of the skin and mucosae constitute a large
group of sometimes devastating diseases, encompassing bullous pemphigoid, gestational …

[HTML][HTML] Update on IgG4-mediated autoimmune diseases: new insights and new family members

I Koneczny - Autoimmunity Reviews, 2020 - Elsevier
Antibodies of IgG4 subclass are exceptional players of the immune system, as they are
considered to be immunologically inert and functionally monovalent, and as such may be …

[HTML][HTML] IL-17A is functionally relevant and a potential therapeutic target in bullous pemphigoid

L Chakievska, MM Holtsche, A Künstner, S Goletz… - Journal of …, 2019 - Elsevier
IL-17A has been identified as key regulatory molecule in several autoimmune and chronic
inflammatory diseases followed by the successful use of anti-IL-17 therapy, eg in ankylosing …

Autoantibody-specific signalling in pemphigus

T Schmitt, J Waschke - Frontiers in Medicine, 2021 - frontiersin.org
Pemphigus is a severe autoimmune disease impairing barrier functions of epidermis and
mucosa. Autoantibodies primarily target the desmosomal adhesion molecules desmoglein …

Structural proteins of the dermal‐epidermal junction targeted by autoantibodies in pemphigoid diseases

S Goletz, D Zillikens, E Schmidt - Experimental dermatology, 2017 - Wiley Online Library
The dermal‐epidermal junction consists of a network of several interacting structural
proteins that strengthen adhesion and mediate signalling events. This structural network …

Anti-p200 pemphigoid

S Goletz, T Hashimoto, D Zillikens, E Schmidt - Journal of the American …, 2014 - Elsevier
Anti-p200 pemphigoid is a rare subepidermal blistering skin disease. Patients'
autoantibodies label the dermal side of 1 mol/L NaCl-split human skin by indirect …

Impact of serum cytokine levels on EEG-measured arousal regulation in patients with major depressive disorder and healthy controls

FM Schmidt, A Pschiebl, C Sander, KC Kirkby… - …, 2016 - karger.com
Background: In major depressive disorder (MDD), findings include hyperstable regulation of
brain arousal measured by electroencephalography (EEG) vigilance analysis and …

Anti-p200 pemphigoid: a systematic review

K Kridin, AR Ahmed - Frontiers in Immunology, 2019 - frontiersin.org
The many clinical aspects of anti-p200 pemphigoid are not well-characterized. We aimed to
analyze and correlate known existing data on the epidemiological, clinical, histological, and …

Bullous pemphigoid induced by IgG targeting type XVII collagen non‐NC16A/NC15A extracellular domains is driven by Fc gamma receptor‐and complement …

M Pigors, S Patzelt, N Reichhelm… - The Journal of …, 2024 - Wiley Online Library
Bullous pemphigoid (BP) is an autoimmune blistering disease characterized by
autoantibodies targeting type XVII collagen (Col17) with the noncollagenous 16A (NC16A) …