[HTML][HTML] Metalloproteins containing cytochrome, iron–sulfur, or copper redox centers

J Liu, S Chakraborty, P Hosseinzadeh, Y Yu… - Chemical …, 2014 - ACS Publications
Redox reactions play important roles in almost all biological processes, including
photosynthesis and respiration, which are two essential energy processes that sustain all life …

Protein design: toward functional metalloenzymes

F Yu, VM Cangelosi, ML Zastrow, M Tegoni… - Chemical …, 2014 - ACS Publications
Protein design is a valuable tool for understanding the fundamental factors that dictate
protein structure and function. The field of protein design has seen significant progress over …

Current state and future perspectives of engineered and artificial peroxygenases for the oxyfunctionalization of organic molecules

MC Sigmund, GJ Poelarends - Nature Catalysis, 2020 - nature.com
Peroxygenases are attractive biocatalysts for the selective introduction of oxygen into
organic molecules under mild conditions with hydrogen peroxide as the oxygen source. In …

Design and engineering of artificial oxygen-activating metalloenzymes

F Nastri, M Chino, O Maglio… - Chemical Society …, 2016 - pubs.rsc.org
Many efforts are being made in the design and engineering of metalloenzymes with catalytic
properties fulfilling the needs of practical applications. Progress in this field has recently …

Biodegradation of aromatic pollutants by metalloenzymes: A structural-functional-environmental perspective

YW Lin - Coordination chemistry reviews, 2021 - Elsevier
Environmental security is closely related to public health. Aromatic pollutants constitute a
class of hazardous environmental chemicals, such as halophenols and polycyclic aromatic …

Studying peptide-metal ion complex structures by solution-state NMR

DE Shalev - International Journal of Molecular Sciences, 2022 - mdpi.com
Metal chelation can provide structural stability and form reactive centers in metalloproteins.
Approximately one third of known protein structures are metalloproteins, and metal binding …

Hydrogen evolution from water catalyzed by cobalt-mimochrome VI* a, a synthetic mini-protein

V Firpo, JM Le, V Pavone, A Lombardi, KL Bren - Chemical Science, 2018 - pubs.rsc.org
A synthetic enzyme is reported that electrocatalytically reduces protons to hydrogen (H2) in
water near neutral pH under aerobic conditions. Cobalt mimochrome VI* a (CoMC6* a) is a …

Engineering metalloprotein functions in designed and native scaffolds

F Nastri, D D'Alonzo, L Leone, G Zambrano… - Trends in biochemical …, 2019 - cell.com
Metalloproteins are crucial for life. The mutual relationship between metal ions and proteins
makes metalloproteins able to accomplish key processes in biological systems, often very …

Control of heme coordination and catalytic activity by conformational changes in peptide–amphiphile assemblies

LA Solomon, JB Kronenberg… - Journal of the American …, 2017 - ACS Publications
Self-assembling peptide materials have gained significant attention, due to well-
demonstrated applications, but they are functionally underutilized. To advance their utility …

Mimochrome, a metalloporphyrin‐based catalytic Swiss knife

L Leone, M Chino, F Nastri, O Maglio… - Biotechnology and …, 2020 - Wiley Online Library
Over the years, mimochromes, a class of miniaturized porphyrin‐based metalloproteins,
have proven to be reliable but still versatile scaffolds. After two decades from their birth, we …