The prefrontal cortex (PFC) serves as the chief executive officer of the brain, controlling the
highest level cognitive and emotional processes. Its local circuits among glutamatergic …

Elucidating the prefrontal cortical microcircuit has been challenging, given its role in multiple
complex behaviors, including working memory, cognitive flexibility, attention, social …

Certain clinical features of schizophrenia, such as working memory disturbances, appear to
emerge from altered gamma oscillatory activity in the prefrontal cortex (PFC). Given the …

The functional integration of external and internal signals forms the basis of information
processing and is essential for higher cognitive functions. This occurs in finely tuned cortical …

γ-frequency oscillations (30-120 Hz) in cortical networks influence neuronal encoding and
information transfer, and are disrupted in multiple brain disorders. While synaptic inhibition …

Cortical interneurons display striking differences in shape, physiology, and other attributes,
challenging us to appropriately classify them. We previously suggested that interneuron …

Theories stipulate that memories are encoded within networks of cortical projection neurons.
Conversely, GABAergic interneurons are thought to function primarily to inhibit projection …

Decreased hippocampal-prefrontal synchrony may mediate cognitive deficits in
schizophrenia, but it remains unclear which cells orchestrate this long-range synchrony …

Cortical neurons process information on multiple timescales, and areas important for
working memory (WM) contain neurons capable of integrating information over a long …

Somatostatin (SST) is a well-known neuropeptide that is expressed throughout the brain. In
the cortex, SST is expressed in a subset of GABAergic neurons and is known as a protein …