Imidazoline receptors historically referred to a family of nonadrenergic binding sites that
recognize compounds with an imidazoline moiety, although this has proven to be an …

Agmatine is an endogenous amine that is synthesized following the decarboxylation of l-
arginine by arginine decarboxylase. Agmatine exists in mammalian brain and has been …

Although nonsteroidal antiinflammatory drugs (NSAIDs) are frequently used for fever and
pain during pregnancy, their possible interaction with perinatal renal injury induced by …

Gene matching shows that Nischarin is a mouse homologue of human imidazoline receptor
antisera-selective (IRAS) protein, a viable candidate of the imidazoline (I1) receptor …

The I1‐imidazoline receptor (I1R) is a proposed target for drug action relevant to blood
pressure and glucose control. The imidazoline receptor antisera‐selected (IRAS) gene, also …

Neurotransmitters are essential in young children for differentiation and neuronal growth of
the developing nervous system. We aimed to identify possible factors related to secondary …

Imidazoline receptor antisera‐selected protein (IRAS) is considered as a candidate for the I1‐
imidazoline receptor (I1R), but the signaling pathway mediated by IRAS remains unknown …

Purpose: To evaluate the neuroprotective effects of Rilmenidine on diabetic peripheral
neuropathy (DPN) in a rat model of diabetes induced by streptozotocin (STZ). Methods: STZ …

In this review, we present evidence for the involvement of imidazoline binding sites (IBS) in
modulating responses to stress, through central control of monoaminergic and hypothalamo …

Imidazoline I1 receptor signaling is associated with pathways that regulate cell viability
leading to varied cell-type specific phenotypes. We demonstrated that the antihypertensive …