[HTML][HTML] Interrelation between ROS and Ca2+ in aging and age-related diseases

CT Madreiter-Sokolowski, C Thomas, M Ristow - Redox biology, 2020 - Elsevier
Abstract Calcium (Ca 2+) and reactive oxygen species (ROS) are versatile signaling
molecules coordinating physiological and pathophysiological processes. While channels …

[HTML][HTML] Brain aging mechanisms with mechanical manifestations

Y Blinkouskaya, A Caçoilo, T Gollamudi… - Mechanisms of ageing …, 2021 - Elsevier
Brain aging is a complex process that affects everything from the subcellular to the organ
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …

[HTML][HTML] Marine algae-derived bioactive compounds: a new wave of nanodrugs?

F Menaa, U Wijesinghe, G Thiripuranathar… - Marine drugs, 2021 - mdpi.com
Marine algae are rich in bioactive nutraceuticals (eg, carbohydrates, proteins, minerals, fatty
acids, antioxidants, and pigments). Biotic (eg, plants, microorganisms) and abiotic factors …

[HTML][HTML] Neurodegenerative diseases–is metabolic deficiency the root cause?

VR Muddapu, SAP Dharshini… - Frontiers in …, 2020 - frontiersin.org
Neurodegenerative diseases, including Alzheimer, Parkinson, Huntington, and amyotrophic
lateral sclerosis, are a prominent class of neurological diseases currently without a cure …

Role of reactive oxygen species in the progression of Alzheimer's disease

S Bhatt, L Puli, CR Patil - Drug Discovery Today, 2021 - Elsevier
Highlights•Oxidative stress is an etiopathogenic event upstream to Aβ-plaques and
neurofibrillary tangles leading to Alzheimer's disease.•Unquenched ROS perturb the …

[HTML][HTML] Reactive oxygen species: beyond their reactive behavior

A Tauffenberger, PJ Magistretti - Neurochemical Research, 2021 - Springer
Cellular homeostasis plays a critical role in how an organism will develop and age.
Disruption of this fragile equilibrium is often associated with health degradation and …

[HTML][HTML] Oxidative stress in cognitive and epigenetic aging: a retrospective glance

A Kandlur, K Satyamoorthy… - Frontiers in Molecular …, 2020 - frontiersin.org
Brain aging is the critical and common factor among several neurodegenerative disorders
and dementia. Cellular, biochemical and molecular studies have shown intimate links …

[HTML][HTML] Effects of the probiotic formulation SLAB51 in in vitro and in vivo Parkinson's disease models

V Castelli, M d'Angelo, F Lombardi, M Alfonsetti… - Aging (albany …, 2020 - ncbi.nlm.nih.gov
Parkinson is a common neurodegenerative disorder, characterized by motor and non-motor
symptoms, including abnormalities in the gut function, which may appear before the motor …

Neuroprotective role of polyphenols against oxidative stress-mediated neurodegeneration

MS Uddin, A Al Mamun, MT Kabir, J Ahmad… - European journal of …, 2020 - Elsevier
Neurodegenerative diseases (NDs) are characterized by disorders with progressive
deterioration of the structure and/or function of neurons. Genetic mutations can lead to many …

Altered metabolism in Alzheimer disease brain: role of oxidative stress

NG Rummel, DA Butterfield - Antioxidants & Redox Signaling, 2022 - liebertpub.com
Significance: Alzheimer disease (AD) is an all-too-common condition in the aging
population. However, aging does not automatically equal neurodegeneration and memory …