We present a review of short-wave infrared (SWIR, defined here as∼ 1000 to 2000 nm)
spectroscopy and imaging techniques for biological tissue optical property characterization …

Atherosclerotic cardiovascular disease results in> 19 million deaths annually, and coronary
heart disease accounts for the majority of this toll. Despite major advances in treatment of …

Background—High-resolution visualization of atherosclerotic plaque morphology may be
essential for identifying coronary plaques that cause acute coronary events. Optical …

Background—Atherosclerotic plaque stability is related to histological composition.
However, current diagnostic tools do not allow adequate in vivo identification and …

Background—Macrophage degradation of fibrous cap matrix is an important contributor to
atherosclerotic plaque instability. An imaging technology capable of identifying …

The ability to diagnose the early onset of disease, rapidly, non-invasively and unequivocally
has multiple benefits. These include the early intervention of therapeutic strategies leading …

Background—Growth of atherosclerotic plaques is accompanied by neovascularization from
vasa vasorum microvessels extending through the tunica media into the base of the plaque …

Objectives: This study sought to determine the impact of short-term intensive statin therapy
on intracoronary plaque lipid content. Background: Statin therapy significantly reduces the …

Objectives: This study sought to assess agreement between an intravascular near-infrared
spectroscopy (NIRS) system and histology in coronary autopsy specimens. Background …

Autoantibodies serve as a diagnostic tool for systemic lupus erythematosus (SLE) and other
autoimmune diseases, but certain autoantibodies are thought to be directly pathogenic in …